Autoimmune Encephalitis With Anti-NMDA Receptor Antibodies Following Herpetic Encephalitis
NCT ID: NCT04339127
Last Updated: 2020-04-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
12 participants
OBSERVATIONAL
2020-04-01
2020-10-01
Brief Summary
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One of the contributing factors of bad prognosis is the development of encephalitis mediated by autoantibodies, most often directed against NMDA receptors, in the weeks following viral encephalitis.
The description of this pathology is recent, the pathophysiology of this process remains poorly understood, and the management of these patients is not yet codified.
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Cohort NMDARE-HSE
Patients developing clinical autoimmune encephalitis with anti-NMDA antibodies after a herpetic encephalitis, managed by the National Reference Center for Paraneoplastic Syndromes and Autoimmune Encephalitis at the Neurological Hospital of Bron.
Description and analysis
Retrospective, non-interventional study, using clinical, biological, radiological and therapeutic data collected during the initial diagnosis and follow-up.
Interventions
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Description and analysis
Retrospective, non-interventional study, using clinical, biological, radiological and therapeutic data collected during the initial diagnosis and follow-up.
Eligibility Criteria
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Inclusion Criteria
* After a herpetic encephalitis documented by a positive viral PCR for HSV in the CSF
* Without age limit
ALL
No
Sponsors
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Hospices Civils de Lyon
OTHER
Responsible Party
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Principal Investigators
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Jérôme Honnorat
Role: STUDY_DIRECTOR
National Reference Center of autoimmune encephalitis
Locations
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Hospice Civils de Lyon
Bron, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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NMDARE-HSE
Identifier Type: -
Identifier Source: org_study_id
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