Damage and Renal Clearance of Glycocalyx in Cardiac Surgery
NCT ID: NCT04332952
Last Updated: 2020-04-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
21 participants
OBSERVATIONAL
2017-08-01
2017-12-31
Brief Summary
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The manipulation of the heart during cardiac surgery stimulates the release of the natriuretic atrial peptide, which causes endothelial wear in patients undergoing extracorporeal circulation. Dilation of the atrium produces natriuretic atrial peptide, which reduces plasma volume by increasing renal excretion and vascular permeability. The atrial peptide degrades the surface of the coronary endothelium, causing loss of the side cam protein nucleus. This study investigates the relationship between clamping time in cardiac surgery and the clearance of endothelial inflammation markers.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Patients who underwent cardiac surgery for a single valve change or replacement
Exclusion Criteria
* Patients with a previous diagnosis of hematological malignancy
* Patients undergoing pulmonary valve change surgery.
* Patients undergoing Bentall and Bono surgery.
* Patients Undergoing Coronary Artery Bypass Surgery
18 Years
ALL
No
Sponsors
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Instituto Nacional de Cardiologia Ignacio Chavez
OTHER
Miguel Ayala León
NETWORK
Responsible Party
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Miguel Ayala León
cardiovascular critical care unit director
Locations
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Hospital Beneficencia Española de Puebla
Puebla City, , Mexico
Countries
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Other Identifiers
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Cardiologia-002
Identifier Type: -
Identifier Source: org_study_id
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