Effect of CI on Prognosis in the Elderly Patients With ACS

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-01

Study Completion Date

2022-06-30

Brief Summary

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This study aims to investigate the incidence and characteristics of cognitive Impairment(CI) in the elderly patients with acute coronary syndrome (ACS), and to determine whether CI are predictive of the prognosis of major adverse cardiovascular events (MACE) and mortality.

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Detailed Description

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Conditions

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Acute Coronary Syndrome Cognitive Impairment Elderly

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Participates

This is an observational study

MMSE and MoCA

Intervention Type DIAGNOSTIC_TEST

This is an observational study. All the patients evaluate with MMSE (Mini-mental State Examination) and MoCA (Montreal Cognitive Assessment), and investigate the incidence and characteristics of cognitive and MACE

Interventions

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MMSE and MoCA

This is an observational study. All the patients evaluate with MMSE (Mini-mental State Examination) and MoCA (Montreal Cognitive Assessment), and investigate the incidence and characteristics of cognitive and MACE

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* ≥65yr
* Confirmed ACS diagnosis （include unstable angina, ST-segment elevation myocardial infarction and Non ST-segment elevation myocardial infarction）
* fulfilled MMSE or MoCA
* patients agreed and provided informed consent

Exclusion Criteria

* Type 2 myocardial infarction and Acute nonischemic myocardial injury
* past history of malignant tumors
* Past history of stroke or dementia
* Hepatic insufficiency (ALT\>8ULN or ALT\>3ULN and TBIL\>2ULN)
* Renal insufficiency (GFR\<15 ml/min/1.73m2)

Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No