Trajectory of Frailty and Cognitive Dysfunction in Older Adults

NCT ID: NCT06276166

Last Updated: 2024-03-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

934 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-15

Study Completion Date

2026-12-31

Brief Summary

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To explore the heterogeneity of the development trend of frailty and cognitive function of older adults.

Detailed Description

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According to the inclusion and exclusion criteria, the older adults will be selected from community health service centers in four districts of Beijing. Frailty and cognitive function of the older adults will be assessed for a 24-month longitudinal multi-time (baseline, 6, 12 and 24 months). The heterogeneity of the development trend of frailty and cognitive function will be explored, and the subgroups of joint development trajectory of frailty and cognitive impairment will be classified, so as to identify high-risk populations that need to be managed.

Conditions

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Frailty Cognitive Dysfunction Community-dwelling Older Adults

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Older adults

Older adults without clear diagnosis of any type of dementia, neurological diseases, and mental disorders that affecting cognitive function.

No intervention

Intervention Type OTHER

No intervention

Interventions

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No intervention

No intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age ≥60 years.
* Older adults with clear consciousness, ability of simple written and verbal communication.
* They volunteered to participate in this study, and signed an informed consent.

Exclusion Criteria

* A clear diagnosis of any type of dementia.
* There are neurological diseases that clearly lead to cognitive dysfunction, such as severe cerebrovascular disease, brain trauma, intracranial tumors, etc.
* They have been clearly diagnosed with mental disorders affecting cognitive function, including schizophrenia, depression, bipolar disorder, etc.
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Zheng Li

OTHER

Sponsor Role lead

Responsible Party

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Zheng Li

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Zheng Li

Role: STUDY_CHAIR

Chinese Academy of Medical Sciences & Peking Union Medical College

Central Contacts

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Zheng Li

Role: CONTACT

13701257650

Other Identifiers

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72374215

Identifier Type: -

Identifier Source: org_study_id

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