Precision Stratification for Frailty and Cognitive Decline

NCT ID: NCT07081282

Last Updated: 2025-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

252 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-01

Study Completion Date

2027-05-31

Brief Summary

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The Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB) trial aim to test the effectiveness of an exercise, cognitive and lifestyle intervention amongst older adults over a 12-weeks trial period to prevent frailty and promote social bonding.

Detailed Description

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In the Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB) trial, participants will use the Care4Seniors 2.0 mobile application, in which physical and cognitive exercises will be provided to participants using this digital technology. Weekly in-person group exercise and cognitive sessions will also be conducted to prevent frailty, promote social bonding, as well as reduce social isolation and loneliness.

In the long term, this new service model has the potential to transform care, contain healthcare cost inflation and increase the efficiency of the lean manpower. It will translate knowledge into practice, resulting in impactful outcomes such as better self-management and healthy longevity. The CIRTAB program will raise the awareness of health behaviour, thus attracting more older adults to engage in preventive health and thus better prepare them for healthy ageing.

Conditions

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Frailty Cognitive Decline

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Intervention Arm

Participants will receive the CIRTAB intervention three times each week over 12-weeks.

Group Type EXPERIMENTAL

Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB)

Intervention Type BEHAVIORAL

Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB)

Active Control

Participants will receive once in centre-based exercise health programme each week over 12-weeks.

Group Type ACTIVE_COMPARATOR

Centre-Based Exercise Health Session

Intervention Type BEHAVIORAL

Participants will receive one time centre-based exercise health programme each week.

Control

Participants will not participate in any exercise-related or brain health-related research studies or centre-based programme during trial period.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB)

Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB)

Intervention Type BEHAVIORAL

Centre-Based Exercise Health Session

Participants will receive one time centre-based exercise health programme each week.

Intervention Type BEHAVIORAL

Other Intervention Names

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CIRTAB

Eligibility Criteria

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Inclusion Criteria

1. Older Adults Aged 60 to 85 years old
2. Living in the community
3. Formally diagnosed with at least one chronic disease
4. Able to communicate in either English or Mandarin

Exclusion Criteria

1. Severe vision or hearing impairment
2. Diagnosed with severe cognitive impairment (e.g. dementia)
3. Diagnosed with severe psychiatric disorders (e.g. psychotic disorders, major depressive disorder)
Minimum Eligible Age

60 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Changi General Hospital

OTHER

Sponsor Role collaborator

National University of Singapore

OTHER

Sponsor Role lead

Responsible Party

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Vivien Xi WU, PhD

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Active Ageing Centres Under Changi General Hospital's Community Health Team Cluster (East Region)

Singapore, , Singapore

Site Status RECRUITING

Countries

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Singapore

Central Contacts

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Vivien Dr Wu

Role: CONTACT

+6566012756

Delphine Ms Chen

Role: CONTACT

Facility Contacts

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Michelle Ms Kee

Role: primary

+6569365827

Other Identifiers

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NUS-IRB-2023-526

Identifier Type: -

Identifier Source: org_study_id

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