Decoding the Cognitive Trajectory of Hong Kong SuperAgers: a Longitudinal Follow-up Study
NCT ID: NCT05728801
Last Updated: 2023-12-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
400 participants
OBSERVATIONAL
2022-06-01
2024-12-01
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Superagers
SuperAgers are determined by the scores of global cognitive function. This ensured that the participants are divided by a measure relevant to the current study without directly biasing the results toward the domain of interest.
Ageing
Using comprehensive cognitive tests to quality the domain-specific cognitive changes during ageing.
Normal ageing elderly
The cases with the scores of cognitive performance within 1.5 standard deviation (SD) of age and education matched normative values derived from our cohort study, of which presented with HK MoCA score greater than 26 and CDR score equal to 0
Ageing
Using comprehensive cognitive tests to quality the domain-specific cognitive changes during ageing.
Neurocognitive disorders patients
NCD patients are defined as: evidence of modest decline in one or more cognitive domains, which is set as ≥ 1.5 SD below the age- and education-adjusted normative scores; no interference with independence in everyday activities; and no comorbid major psychiatric disorders.
Ageing
Using comprehensive cognitive tests to quality the domain-specific cognitive changes during ageing.
Interventions
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Ageing
Using comprehensive cognitive tests to quality the domain-specific cognitive changes during ageing.
Eligibility Criteria
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Inclusion Criteria
* Normal aging: the cases with the scores of cognitive performance within 1.5 standard deviation (SD) of age and education matched normative values derived from our cohort study, of which presented with HK MoCA score greater than 26 and CDR score equal to 0;
* NCD patients are defined as: evidence of modest decline in one or more cognitive domains, which is set as ≥ 1.5 SD below the age- and education-adjusted normative scores; no interference with independence in everyday activities; and no comorbid major psychiatric disorders.
Exclusion Criteria
* History of major neurological deficits including stroke, transient ischemic attack or traumatic brain injury;
* Comorbidities with depressive symptoms.
60 Years
95 Years
ALL
Yes
Sponsors
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Chinese University of Hong Kong
OTHER
Responsible Party
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LU Hanna
Assistant Professor
Principal Investigators
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Hanna LU, PhD
Role: PRINCIPAL_INVESTIGATOR
Chinese University of Hong Kong
Locations
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Tai Po Hospital
Hong Kong, , Hong Kong
Countries
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Central Contacts
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Facility Contacts
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Candy Wong
Role: primary
Related Links
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Hong Kong SuperAgers
Other Identifiers
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2019.078
Identifier Type: -
Identifier Source: org_study_id