Comparison of Rocuronium Induced Neuromuscular Blockade in Late Second Trimester Pregnant and Non-pregnant Women

NCT ID: NCT04253093

Last Updated: 2020-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-08-01

Study Completion Date

2020-12-01

Brief Summary

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The present study is to compare the onset and duration of rocuronium in late second trimester women and non-pregnant women undergoing general anesthesia.

Detailed Description

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Pregnancy induces physiological changes. Plasma volume, cardiac output, hepatic blood flow and protein binding are changed from the first trimester of pregnancy. These physiological changes give effect to the onset and duration of neuromuscular blocking drugs.

Rocuronium is a commonly used neuromuscular blocking drug categorized as FDA category B. Rocuronium is widely used for pregnant women. Previous studies have evaluated the onset and duration of rocuronium in postpartum women. Lately, the investigators have evaluated the onset and duration of rocuronium in early second trimester pregnant women and the duration was significantly longer in early second trimester women compared to non-pregnant women.

Since there is little research on the onset and duration of rocuronium in the late second trimester pregnant women, the investigators planned the present research.

Conditions

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Pregnancy Related

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* women undergoing general anesthesia

Exclusion Criteria

* liver disease
* renal disease
* diabetes mellitus
* asthma
* allergic to specific drugs
* BMI\>30 or \<18
Minimum Eligible Age

20 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Hallym University Kangnam Sacred Heart Hospital

OTHER

Sponsor Role lead

Responsible Party

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Choi Eun MI

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Eunmi Choi

Role: STUDY_CHAIR

professor

Locations

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Kangnam sungshim hospital

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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InJung Jun

Role: CONTACT

82-10-9312-0162

Facility Contacts

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Jun In-Jung

Role: primary

Other Identifiers

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2019-05-008

Identifier Type: -

Identifier Source: org_study_id

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