Evaluation of Different Anesthesia for Uterine Curettage

NCT ID: NCT00733564

Last Updated: 2009-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-08-31

Study Completion Date

2009-03-31

Brief Summary

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Anesthesia during uterine curettage is a problem. Paracervical block is used in general for such an operation, though, the anesthetic efficacy is incomplete. Propofol is the short-lasting intravenous anesthetic administrated popularly. Sevoflurane is a new inhalational anesthetic well-known for it's "easy come, easy go" property. The investigators hypothesized that propofol, sevoflurane and paracervical block had different anesthetic efficacy during uterine curettage. Which one is the optimal selection for such operation needed to be evaluated.

Detailed Description

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Conditions

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Uterine Curettage Abortion, Induced

Keywords

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Local anesthetic Propofol Sevoflurane

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

Paracervical block will be performed

Group Type ACTIVE_COMPARATOR

Lidocaine

Intervention Type DRUG

Paracervical injection of 2% Lidocaine to block associated nociception input

2

Propofol anesthesia will be performed

Group Type EXPERIMENTAL

Propofol

Intervention Type DRUG

Propofol 3mg/kg will be injected intravenously; 1 mg/kg will be added additionally for incomplete anesthesia

3

Sevoflurane anesthesia will be performed

Group Type EXPERIMENTAL

Sevoflurane

Intervention Type DRUG

Sevoflurane 8% for anesthesia induction, 2-3% as the maintenance

Interventions

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Lidocaine

Paracervical injection of 2% Lidocaine to block associated nociception input

Intervention Type DRUG

Propofol

Propofol 3mg/kg will be injected intravenously; 1 mg/kg will be added additionally for incomplete anesthesia

Intervention Type DRUG

Sevoflurane

Sevoflurane 8% for anesthesia induction, 2-3% as the maintenance

Intervention Type DRUG

Other Intervention Names

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Lignocaine Diprivan Sevorane

Eligibility Criteria

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Inclusion Criteria

* ASA status I-II
* Performing abortion operation (medical- or surgical)
* Requiring painless abortion

Exclusion Criteria

* \< 19 yrs, and \>=45 yrs
* History of central active drugs administration
* Drug abuse
* Hypertension
* Diabetes
* Any other chronic diseases
* Allergy to the study drugs
* Habit of over-volume alcohol drinking
* Records of history of centrally active drug use and psychiatry
* Any organic disorder
Minimum Eligible Age

19 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Nanjing Medical University

OTHER

Sponsor Role lead

Responsible Party

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Nanjing Medical University

Principal Investigators

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XiaoFeng Shen, MD

Role: STUDY_DIRECTOR

Nanjing Medical University

Locations

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Nanjing Maternal and Child Health Care Hospital

Nanjing, Jiangsu, China

Site Status

Countries

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China

Other Identifiers

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NJFY0890-MZ12

Identifier Type: -

Identifier Source: secondary_id

NMU-FY2008-209

Identifier Type: -

Identifier Source: org_study_id