Timing of Rocuronium After Induction With Propofol on Temporal Summation of Pain
NCT ID: NCT04547608
Last Updated: 2020-09-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
100 participants
INTERVENTIONAL
2020-05-01
2020-09-04
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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group PRi
received immediate injection of rocuronium after propofol administration,
The difference of the timing of rocuronium administration after propofol injection
The difference of the timing was rocuronium was administered immediately after propofol injection or when BIS score became below 60 after propofol administration.
group PRd
rocuronium injection when bispectral index score became below 60 after propofol administration
The difference of the timing of rocuronium administration after propofol injection
The difference of the timing was rocuronium was administered immediately after propofol injection or when BIS score became below 60 after propofol administration.
Interventions
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The difference of the timing of rocuronium administration after propofol injection
The difference of the timing was rocuronium was administered immediately after propofol injection or when BIS score became below 60 after propofol administration.
Eligibility Criteria
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Inclusion Criteria
* American Society of Anesthesiologists' physical status class) I-II
Exclusion Criteria
* Patients who had muscular, cardiovascular, hepatic or kidney disorders and patients with a history of medication who would affect muscle relaxants were excluded from this study.
* Patients with difficult venous access on forearm, a known allergy to propofol or rocuronium, chronic pain, pregnancy, and those who had received analgesics or sedatives within the previous 24 hours, were excluded from the study.
19 Years
60 Years
FEMALE
Yes
Sponsors
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Wonkwang University Hospital
OTHER
Responsible Party
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Cheol Lee
Professor
Principal Investigators
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Cheol Lee, M.D,Ph.D
Role: STUDY_DIRECTOR
Department of anesthesiology and pain medicine
Locations
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WonwangUH
Iksan, Jeollabuk-do, South Korea
Countries
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References
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Cheng JC, Erpelding N, Kucyi A, DeSouza DD, Davis KD. Individual Differences in Temporal Summation of Pain Reflect Pronociceptive and Antinociceptive Brain Structure and Function. J Neurosci. 2015 Jul 1;35(26):9689-700. doi: 10.1523/JNEUROSCI.5039-14.2015.
Ayoglu H, Altunkaya H, Ozer Y, Yapakci O, Cukdar G, Ozkocak I. Does dexmedetomidine reduce the injection pain due to propofol and rocuronium? Eur J Anaesthesiol. 2007 Jun;24(6):541-5. doi: 10.1017/S0265021506002250. Epub 2007 Jan 23.
Hwang SM, Cho SH, Lim SY, et al. The efficacy of BIS monitoring for the preventing of withdrawal movement on the intravenous injection of rocuronium. Korean J Anesthesiol 2005;49:293-7.
Lim BG, Lee IO, Kim YS, Won YJ, Kim H, Kong MH. The utility of bispectral index monitoring for prevention of rocuronium-induced withdrawal movement in children: A randomized controlled trial. Medicine (Baltimore). 2017 Jan;96(2):e5871. doi: 10.1097/MD.0000000000005871.
Other Identifiers
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WonkwangUH7
Identifier Type: -
Identifier Source: org_study_id
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