Effect of Laparoscopic Operation on Rocuronium and Cisatracurium: Pharmacokinetic and Pharmacodynamic Analysis
NCT ID: NCT02194855
Last Updated: 2020-08-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
100 participants
INTERVENTIONAL
2015-01-01
2016-06-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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laparoscopic operation on rocuronium
according different surgical type, all patients were divided into 2 groups: the laparoscopic surgery group and open surgery group.Each group were randomly assigned to the rocuronium group and cisatracurium group.
rocuronium
Rocuronium 0.6 mg.kg-1 was administered within 5 s as an intravenous bolus
laparoscopic operation on cisatracurium
according different surgical type, all patients were divided into 2 groups: the laparoscopic surgery group and open surgery group.Each group were randomly assigned to the rocuronium group and cisatracurium group.
cisatracurium
cisatracurium 0.15mg.kg-1 was administered within 5 s as an intravenous bolus
conventional open surgery on rocuronium
according different surgical type, all patients were divided into 2 groups: the laparoscopic surgery group and open surgery group.Each group were randomly assigned to the rocuronium group and cisatracurium group.
rocuronium
Rocuronium 0.6 mg.kg-1 was administered within 5 s as an intravenous bolus
conventional open surgery on cisatracurium
according different surgical type, all patients were divided into 2 groups: the laparoscopic surgery group and open surgery group.Each group were randomly assigned to the rocuronium group and cisatracurium group.
cisatracurium
cisatracurium 0.15mg.kg-1 was administered within 5 s as an intravenous bolus
Interventions
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rocuronium
Rocuronium 0.6 mg.kg-1 was administered within 5 s as an intravenous bolus
cisatracurium
cisatracurium 0.15mg.kg-1 was administered within 5 s as an intravenous bolus
Eligibility Criteria
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Inclusion Criteria
* BMI 18-30 kg.m-2
* elective gynaecological operations under general anaesthesia
Exclusion Criteria
* hepatitis
* hepatoma
* heart failure
* arrhythmia
* renal dysfunction
* electrolyte disturbances
* acid-base imbalances
* neuromuscular disorders
18 Years
60 Years
FEMALE
No
Sponsors
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Fudan University
OTHER
Responsible Party
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Tingting Wang
Tingting Wang
Principal Investigators
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Shaoqiang Huang, doctor
Role: PRINCIPAL_INVESTIGATOR
Obstetrics and Gynecology,Fudan University
Other Identifiers
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TingtingWang
Identifier Type: -
Identifier Source: org_study_id
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