Analysis of the Glycemic Profile of People Suffering From Compulsive Eating Disorders Aiming to Offer an Innovative Nutritional Approach (GLUCOPULSE)

NCT ID: NCT04211818

Last Updated: 2025-09-30

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 20 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2020-10-16
• Study Completion Date: 2023-07-01

Brief Summary

Eating Disorders (ED) are a major public health problem. Current care remains only partially effective and the pathophysiology of the disorders remains to be deepened. With regard to compulsive ED (bulimia and binge eating disorder), our clinical experience suggests that one of the major triggers for crisis may be related to glycemia. In fact, bulimia could be considered as a vicious circle where the binge eating disorder is going to be followed by a food restriction in order to control weight , putting the subject in a situation of "energy deficiency" which will favor the emergence of new crises . Technological advances have resulted in the emergence of new measuring devices, such as "tracking", which records continuous glycemia, which would allow us to explore these clinical hypotheses.

Detailed Description

This is an open-label, exploratory, proof-of-concept study.

20 patients will be recruited from the day hospital of the Endocrinology and Nutrition Department of the University Hospital of Montpellier, Lapeyronie and from Emergencies and Post-psychiatric Emergencies Department.

During the inclusion visit, the dietician will explain to the patient the use of the dietary book and the glycemic sensor which will be allocated to it. The patient will also answer to self-questionnaires about his eating behavior.

No nutritional approach will be addressed so as not to alter the patient's eating behavior and not to influence the results.

They will be followed-up during 14 days.

Conditions

Bulimia; Binge Eating; Blood Glucose, Low; Crisis State; Compulsion

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Patients

Group Type: EXPERIMENTAL

Eating Behavior

Intervention Type: BEHAVIORAL

A dietary book will be given to the patient and will be filled by this one during 14 days

Blood glucose records

Intervention Type: BIOLOGICAL

A glycemic sensor will be placed at the back of the patient's arm

Interventions

Eating Behavior

A dietary book will be given to the patient and will be filled by this one during 14 days

Intervention Type: BEHAVIORAL

Blood glucose records

A glycemic sensor will be placed at the back of the patient's arm

Intervention Type: BIOLOGICAL

Eligibility Criteria

Inclusion Criteria

• Subject suffering from eating disorders with at least 3 episodes of bulimia per week for at least 2 months
• Subject affiliated to a health insurance or beneficiary of such a plan
• Subject able to understand the nature, purpose and methodology of the study
• Subject signed informed consent

Exclusion Criteria

• Subject suffering from eating disorders such as anorexia nervosa
• Subject unable according to the investigator's opinion to keep updated a dietary book or to perform correctly the glycemic recordings
• Subject suffering from somatic pathology (ex: diabetes) or psychiatric pathology assessed by the MINI (ex : severe current major depressive episode) that may interfere with the protocol according to the the investigator
• Major subject legally protected (guardians or curators) or deprived of freedom by judicial or administrative order
• Pregnant or nursing woman

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Montpellier

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

University Hospital

Montpellier, , France

Countries

France

Other Identifiers

RECHMPL18_0470

Identifier Type: -

Identifier Source: org_study_id