Effects of a Caffeine- and Protein-Containing Coffee Beverage on Metabolism and Muscular Performance

NCT ID: NCT04180787

Last Updated: 2020-05-07

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 19 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-12-05
• Study Completion Date: 2020-03-09

Brief Summary

The purpose of this randomized, double-blind, crossover study is to investigate the effects of Bang® Keto Coffee on resting and post-exercise metabolism and muscular performance during lower body resistance exercise.

Detailed Description

Resistance-trained males and females will be recruited for participation in a randomized, double-bind, crossover trial. After providing informed consent, each participant will undergo a familiarization session to become accustomed to the study procedures. Following familiarization, each participant will complete two laboratory visits consisting of metabolism and exercise performance assessments. In both visits, a baseline assessment of resting metabolic rate (RMR) and respiratory exchange ratio (RER) will be conducted using indirect calorimetry. Following the initial RMR assessment, each participant will ingest a coffee flavored beverage, either VPX Bang® Keto Coffee or a flavor-matched placebo. After beverage consumption, the participant will return to the supine position and rest prior to initiation of the second RMR assessment. Immediately following the second RMR assessment, the participant will begin a 5-minute dynamic bodyweight warm up. Participants will then begin squat testing procedures on a mechanized squat device. After completing the squat testing, participants will complete a standard 1-repetition maximum and repetitions to failure using a plate-loaded hip sled machine. Following the hip sled testing, participants will repeat the mechanized squat testing. Following completion of the exercise testing, a third and final RMR assessment will be performed. Following successful completion of the first condition, each participant will enter a wash out period, after which the visit will be repeated with ingestion of the alternative beverage.

Conditions

Exercise Performance; Metabolism

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: OTHER
• Blinding Strategy: TRIPLE

Study Groups

Keto Coffee

VPX Bang® Keto Coffee beverage

Group Type: EXPERIMENTAL

Beverage Consumption

Intervention Type: DIETARY_SUPPLEMENT

Participants will consume either VPX Bang® Keto Coffee beverage or flavor-matched placebo beverage in each condition.

Placebo

Flavor-matched placebo beverage

Group Type: PLACEBO_COMPARATOR

Beverage Consumption

Intervention Type: DIETARY_SUPPLEMENT

Participants will consume either VPX Bang® Keto Coffee beverage or flavor-matched placebo beverage in each condition.

Interventions

Beverage Consumption

Participants will consume either VPX Bang® Keto Coffee beverage or flavor-matched placebo beverage in each condition.

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• Between the ages of 18 and 40
• Generally healthy (defined as an absence of any disease or medical condition which could potentially be negatively affected by consumption of the commercially available dietary supplement of performance of exercise, including but not limited to musculoskeletal or cardiovascular diseases).
• Resistance-trained, defined as completing 3+ resistance training sessions per week for at least one year and including at least weekly training of the lower body through a multi-joint exercise such as the squat or leg press.
• Regular caffeine consumption, defined as an average self-reported daily intake of 200+ mg of caffeine, which is equivalent to approximately 2 cups of coffee.

• Pregnant or breastfeeding (for female participants)
• Taking prescription medication which could reasonably make participation unsafe for the participant or influence study outcomes
• An inability to complete lower body resistance exercise due to injury or medical condition
• Self-reported caffeine sensitivity, as indicated by unwanted side effects when caffeine is consumed.
• Allergy to any of the ingredients in the commercially available dietary supplement
• Self-reported claustrophobia (due to metabolism testing)

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Vital Pharmaceuticals, Inc.

UNKNOWN

Sponsor Role: collaborator

Texas Tech University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Grant M Tinsley, PhD

Role: PRINCIPAL_INVESTIGATOR

Texas Tech University

Locations

Department of Kinesiology & Sport Management

Lubbock, Texas, United States

Countries

United States

References

Harty PS, Stratton MT, Escalante G, Rodriguez C, Dellinger JR, Williams AD, White SJ, Smith RW, Johnson BA, Sanders MB, Tinsley GM. Effects of Bang(R) Keto Coffee Energy Drink on Metabolism and Exercise Performance in Resistance-Trained Adults: A Randomized, Double-blind, Placebo-controlled, Crossover Study. J Int Soc Sports Nutr. 2020 Aug 24;17(1):45. doi: 10.1186/s12970-020-00374-5.

Reference Type: DERIVED

PMID: 32831109 (View on PubMed)

Other Identifiers

20-0130

Identifier Type: -

Identifier Source: org_study_id