The Long-term Effects of Oceanix™ on Resistance Training Adaptations
NCT ID: NCT04136821
Last Updated: 2020-02-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
25 participants
INTERVENTIONAL
2019-09-30
2020-01-31
Brief Summary
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Detailed Description
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This study will be a double blind parallel, randomized placebo-controlled trial. The investigators will request participation from 25 male and female participants (40-60 % mixture of each) ranging from 18 to 45 years old who are active (i.e. 30 minutes per week of vigorous activity classified as greater than 75 % of their HR max 3 days • week-1). The exclusion criteria will include having a BMI of 30 or more kg/m²; having cardiovascular, metabolic, or endocrine disease; undergone surgery that affects digestion and absorption, smoking, drinking heavily (\> 7 and \> 14 drinks per week for women and men, respectively), women who are pregnant or planning to be pregnant; taking medication to control blood pressure, lipids, and blood glucose; have taken or currently taking anabolic-androgenic steroids. The investigators will also exclude individuals using antioxidant supplements, NSAIDS, or nutritional supplements known to stimulate recovery or muscle mass gains, heart disease, prescription medications, dietary supplements that enhance body strength, muscle, immune function, muscle recovery, or soreness. Additionally, individuals cannot have allergies for seaweeds or marine sources or any dietary supplements or take any psychiatric supplements or blood thinners.
Participants will be baselined and post-tested at week zero and again after 6 weeks of training, respectively. However, on weeks 2 and 5, participants will experience an overreaching phase to induce stress, and run through specific tests to gauge recovery at the end of those specific weeks. Variables collected at these time points are described below.
Primary variables:
* Muscle, fat mass, and bone density as indicated on DXA
* Upper body strength, velocity, and power on the bench press.
* Lower body strength and power on a dual force plate.
* Vertical jump performance on a dual force plate.
* Movement mechanics and stability using a combination of motion analysis and a dual force plate.
Secondary Variables
* CBC, CMP, Urinalysis
* Vital signs (blood pressure)
* Adverse Events Scale
* PRS and RPE scales
At the end of weeks 2 and 5 participants will be examined for their perceived recovery, soreness, serum markers of muscle damage (creatine kinase), and oxidative stress markers (SOD and Total Antioxidant Status). The rationale for the time points is to introduce extreme stressors in the early and late stages of the training protocol. Variables collected at these time points are described below.
Secondary variables
* Muscle damage (blood creatine kinase), soreness, and recovery.
* Immune function (IGA) , endocrine function (cortisol and testosterone), and oxidative stress (SOD and total antioxidant status).
* PRS scale
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Placebo
Participants will engage in a 6 week, whole-body, resistance training program 3-5 days per week will consuming a visually identical placebo (25mg hydroxypropyl methylcellulose) 30 minutes prior to exercise on training days or with the first meal of the day on non-training days.
Resistance Training
6 weeks of supervised and programmed whole body resistance training, performed 3-5 times per week.
Oceanix™
Participants will engage in a 6 week, whole-body, resistance training program 3-5 days per week will consuming a the treatment condition (Oceanix™) 30 minutes prior to exercise on training days or with the first meal of the day on non-training days.
Oceanix
Ingredient contains highly active antioxidant enzymes, including superoxide dismutase (SOD), as well as essential fatty acids, vitamins, amino acids and minerals.
Resistance Training
6 weeks of supervised and programmed whole body resistance training, performed 3-5 times per week.
Interventions
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Oceanix
Ingredient contains highly active antioxidant enzymes, including superoxide dismutase (SOD), as well as essential fatty acids, vitamins, amino acids and minerals.
Resistance Training
6 weeks of supervised and programmed whole body resistance training, performed 3-5 times per week.
Eligibility Criteria
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Inclusion Criteria
* Volunteers are deemed active if they engage in 30 minutes of vigorous activity, classified as greater than 75 % of their HR max, 3 days • week-1.
Exclusion Criteria
* Cardiovascular, metabolic, or endocrine disease
* Undergone surgery that affects digestion and absorption
* Smoking
* Drinking heavily (\> 7 and \> 14 drinks per week for women and men, respectively)
* Women who are pregnant or planning to be pregnant
* Taking medication to control blood pressure, lipids, and blood glucose
* Have taken or currently taking anabolic-androgenic steroids
* Individuals using antioxidant supplements, NSAIDS, or nutritional supplements known to stimulate recovery or muscle mass gains, heart disease, prescription medications, dietary supplements that enhance body strength, muscle, immune function, muscle recovery, or soreness
* Allergies for seaweeds or marine sources
18 Years
45 Years
ALL
Yes
Sponsors
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Lonza Ltd.
INDUSTRY
Applied Science & Performance Institute
INDUSTRY
Responsible Party
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Locations
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Applied Science & Performance Institute
Tampa, Florida, United States
Countries
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Other Identifiers
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ASPI0519
Identifier Type: -
Identifier Source: org_study_id
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