Remineralization Effect of Fluoride Varnishes on Permanent Molars
NCT ID: NCT04124887
Last Updated: 2019-10-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2017-02-03
2018-02-15
Brief Summary
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Group 1: Duraphat Varnish containing 5% NaF (Colgate-Palmolive, NSW, Australia) (n = 35), Group 2: Clinpro™ White Varnish containing 5% NaF with TCP (3M ESPE, MN, USA) (n = 35), Group 3: Embrace ™ Varnish containing 5% NaF with CXP (Pulpdent, MA, USA) (n = 35), Group 4: MI Varnish containing 5% NaF with CPP-ACP (GC, Tokyo, Japan) (n = 35). All dental treatments of the patients were completed before the varnish application and oral hygiene instructions were given to all children at the start of the study.
Patients were called for follow up appointments at 1, 3 and 6 months, and in the follow-up period DIAGNOdent device (laser fluorescence scanning) was used to monitor mineralization changes. LF measurements were made at baseline (T0), after one month (T1) three months (T2) and six months (T3). Within and between group comparisons were analysed statistically.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Sodium fluoride
Duraphat Varnish containing 5% Sodium fluoride
Sodium Fluoride
Sodium Fluoride varnish was applied to the targeted teeth at baseline, one and three months.
Tricalcium phosphate
Clinpro™ White Varnish containing 5% NaF with TCP
Tricalcium Phosphate
Varnish with Tricalcium Phosphate was applied to the targeted teeth at baseline, one and three months.
Xylitol-coated calcium and phosphate
Embrace ™ Varnish containing 5% NaF with CXP
Xylitol-coated calcium and phosphate
Varnish with Xylitol-coated calcium and phosphate was applied to the targeted teeth at baseline, one and three months.
Casein phosphopeptide amorphous calcium phosphate
MI Varnish containing 5% NaF with CPP-ACP
Casein phosphopeptide amorphous calcium phosphate
Varnish with Casein phosphopeptide amorphous calcium phosphate was applied to the targeted teeth at baseline, one and three months.
Interventions
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Sodium Fluoride
Sodium Fluoride varnish was applied to the targeted teeth at baseline, one and three months.
Tricalcium Phosphate
Varnish with Tricalcium Phosphate was applied to the targeted teeth at baseline, one and three months.
Xylitol-coated calcium and phosphate
Varnish with Xylitol-coated calcium and phosphate was applied to the targeted teeth at baseline, one and three months.
Casein phosphopeptide amorphous calcium phosphate
Varnish with Casein phosphopeptide amorphous calcium phosphate was applied to the targeted teeth at baseline, one and three months.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
6 Years
7 Years
ALL
Yes
Sponsors
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Kırıkkale University
OTHER
Responsible Party
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Merve Erkmen Almaz
Asist prof
Locations
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Kırıkkale University
Kırıkkale, , Turkey (Türkiye)
Countries
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Other Identifiers
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Kırıkkale pedodontics
Identifier Type: -
Identifier Source: org_study_id
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