Contributing Factors to Anterior Resection Syndrome and Its Impact on Quality of Life: A Retrospective Cohort Study

NCT ID: NCT04114591

Last Updated: 2019-10-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

179 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-07-01

Study Completion Date

2019-01-30

Brief Summary

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This study adds to the understanding of the contributing factors leading to LARS, the long term effects of this syndrome post-operatively and its impact on quality of life.

Detailed Description

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Conditions

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Low Anterior Resection Syndrome Cancer Quality of Life

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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LARS symptoms

Patient suffering from LARS as identified through LARS questionnaire

anterior resection

Intervention Type PROCEDURE

The distance from anal verge, preoperative radiotherapy and presence of stoma were analysed

No LARS symptoms

Absence of LARS symptoms

anterior resection

Intervention Type PROCEDURE

The distance from anal verge, preoperative radiotherapy and presence of stoma were analysed

Interventions

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anterior resection

The distance from anal verge, preoperative radiotherapy and presence of stoma were analysed

Intervention Type PROCEDURE

Other Intervention Names

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radiotherapy +/- chemotherapy

Eligibility Criteria

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Inclusion Criteria

* All adult patients \>18 years, under the care of all surgical firms at Mater Dei Hospital, who had undergone anterior resection for rectal cancer between January 2014 and December 2016

Exclusion Criteria

* colorectal cancer (\>15cm) from anal verge
* permanent stoma
* known disseminated or recurrent disease,
* patient without restitution of bowel continuity after 1 year
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Malta

OTHER

Sponsor Role lead

Responsible Party

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Svetlana Doris Brincat

Surgical trainee

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Svetlana Doris Brincat

Role: PRINCIPAL_INVESTIGATOR

Mater Dei Hospital

Locations

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Mater Dei Hospital

Valletta, , Malta

Site Status

Countries

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Malta

Other Identifiers

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S07/18

Identifier Type: -

Identifier Source: org_study_id

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