Lymph Node Ratio as a Predictor for Outcome in Rectal Cancer

NCT ID: NCT05221684

Last Updated: 2022-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-09

Study Completion Date

2022-12-31

Brief Summary

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This study aims to evaluate the value of the LNR as a prognostic indicator in patients with rectal cancer who offered total mesorectal excision.

Detailed Description

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Patients and methods Study design and setting This is a retrospective review of prospectively collected and maintained database of patients with CRC admitted in the Oncology Center of Mansoura University (OCMU), the Colorectal Surgery Unit of Mansoura University Hospitals, and the Department of General Surgery of Alexandria University.

Selection criteria Patients of either gender aged 18 years or above who presented with rectal cancer of any stage will be included in the study. We will exclude patients with patients younger than 18 years; patients with synchronous colon cancer; synchronous liver, pulmonary or bones metastasis; or synchronous gastrointestinal cancer; or patients who were lost to follow-up.

Study endpoints The primary endpoint of the study is to assess the value of lymph node ratio (LNR) on the oncological outcomes.

Conditions

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Recurrence

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Lymph node harvesting

Lymph node harvesting after radical resection for rectal cancer with curative intent

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* rectal cancer of TNM stage I-III
* underwent radical resection with curative intent

Exclusion Criteria

* synchronous colon cancer
* synchronous gastrointestinal cancer
* underwent palliative resection
* presented with intestinal obstruction
* those lost to follow-up.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mansoura University

OTHER

Sponsor Role lead

Responsible Party

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Mostafa shalaby, MD, MSc, PhD

Lecturer of Colorectal Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mostafa Shalaby

Role: PRINCIPAL_INVESTIGATOR

Mansoura Faculty of Medicine

Locations

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Mansoura Faculty of Medicine

Al Mansurah, Dakahliya, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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LN ratio in rectal cancer

Identifier Type: -

Identifier Source: org_study_id

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