Tumor Deposits in Colorectal Cancer and Its Prognostic Value in Survival and Metastasis

NCT ID: NCT06884839

Last Updated: 2025-03-19

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 30 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-08-01
• Study Completion Date: 2025-08-01

Brief Summary

This study aims to evaluate the tumor deposits in colorectal cancer and its prognostic value in survival and metastasis

Detailed Description

Tumor deposits (TDs) are defined as isolated tumor foci found in the pericolonic or perirectal fat or the adjacent mesentery (mesocolonic fat) away from the invasive margin of the tumor without evidence of residual lymphatic tissue. TDs are significantly correlated with poor prognosis after colorectal cancer surgery.

Conditions

Tumor Deposits; Colorectal Cancer; Prognosis; Survival; Metastasis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Therapeutic resection group

Patients with colorectal cancer underwent therapeutic resection with pathologically positive tumor deposits (TDs) to determine distant metastasis occurrence and the effect of TDs on survival.

Therapeutic resection

Intervention Type: PROCEDURE

Patients with colorectal cancer underwent therapeutic resection with pathologically positive tumor deposits (TDs) to determine distant metastasis occurrence and the effect of TDs on survival.

Interventions

Therapeutic resection

Patients with colorectal cancer underwent therapeutic resection with pathologically positive tumor deposits (TDs) to determine distant metastasis occurrence and the effect of TDs on survival.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Age above 18 years old.
• Both sexes.
• All Colorectal cancer patients From Stage I to III Colorectal cancer with pathologically positive Tumor deposits.

Exclusion Criteria

• Patient took neoadjuvant therapy.
• No information available on tumor deposits.
• Colorectal cancer is not the only primary cancer.
• Patients with incomplete information about follow-up.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Minia University

OTHER

Sponsor Role: lead

Responsible Party

Abdelrahman Mohamed Salah

Lecturer of General Surgery, Faculty of Medicine, Minia University, Minia, Egypt.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Minia University

Minya, , Egypt

Site Status: RECRUITING

Countries

Egypt

Central Contacts

Abdelrahman M Salah, MD

Role: CONTACT

Abdelrahman.salah@mu.edu.eg

00201064746493

Facility Contacts

Abdelrahman M Salah, MD

Role: primary

Abdelrahman.salah@mu.edu.eg

00201064746493

Other Identifiers

1267/09/2024

Identifier Type: -

Identifier Source: org_study_id