Registry for Patients Undergoing AUS Surgery for Female SUI Due to ISD

NCT ID: NCT04114266

Last Updated: 2025-08-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

180 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-23

Study Completion Date

2026-04-20

Brief Summary

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Prospective collection of pre-defined parameters of AUS Surgery for Female Stress Urinary Incontinence due to Intrinsic Sphincter Deficiency

Detailed Description

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This will be a prospective non-controlled cohort study evaluating the outcomes of artificial urinary sphincter (AUS) implantation surgery (Robot-assisted, Laparoscopic, Open or other) in female patients. The data collection will be undertaken from multiple centres in Europe. The participation will be by open invitation from the Urologists from the European Society of Female \& Functional Urology Section of the European Association of Urology (ESFFU) to all its members along with other surgeons undertaking these procedures. The aim is to recruit a total of 150 patients in 2 years whereafter patients will be followed until the end of Registry which is 5 years after inclusion of the first patient. There will be no restriction on the number of patients enrolled as long as they are consecutive. The aim is to have a long-term collection of the dataset from as many centres as possible.

An initial assessment for the robustness of the data collection and first clinical evaluation of the data collected will be performed after 1 year by a nominated steering committee. Thereafter, the evaluations will be performed after every year until end of Registry.

Conditions

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Urinary Incontinence Urinary Incontinence, Stress Lower Urinary Tract Symptoms Urination Disorders Urologic Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Questionnaires on Urinary Incontinence-, Sex Function- and Quality of Life (ICIQ-UI-SF, ICIQ-FLUTSsex, ICIQ-LUTSqol, PGI-I)

Artificial Urinary Sphincter Surgery (Robot-assisted, Laparoscopic, Open, or other) for Female Stress Urinary Incontinence due to intrinsic sphincter deficiency is according to standard practice. Patients scheduled for this type of surgery will be asked to participate in this Registry.

At baseline and follow-up, the patients will be required to fill in Questionnaires, i.e. ICIQ -Urinary Incontinence - Short Form (ICIQ-UI-SF), ICIQ Female Sexual Matters associated with Lower Urinary Tract Symptoms ( ICIQ-FLUTSsex), ICIQ Lower Urinary Tract Symptoms Quality of Life (ICIQ-LUTSqol), Patient Global Impression of Improvement-I (PGI-I) which are commonly used in daily practice to assess urinary incontinence, sexual function and quality of life. During the yearly visits, patients will not be required to come for a clinical visit as the questionnaires and a Follow-up form can be completed by post, e-mail or phone call.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient should be Female and aged over 18 years.
* The patient will undergo an initial AUS implantation surgery (Robot-assisted, Laparoscopic, Open or other) for treatment of stress urinary incontinence due to intrinsic sphincter deficiency.
* Participant is willing and able to give informed consent for participation in the Registry
* Patient is able to complete the questionnaires.

Exclusion Criteria

\- Participating center is unable to contribute consecutive patients.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role collaborator

European Association of Urology Research Foundation

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Benoit Peyronnet, Dr.

Role: PRINCIPAL_INVESTIGATOR

Rennes University Hospital

Locations

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Universitair Ziekenhuis Gent

Ghent, , Belgium

Site Status

University Hospital Leuven

Leuven, , Belgium

Site Status

Thomayer Hospital

Prague, , Czechia

Site Status

University Hospital Bordeaux

Bordeaux, , France

Site Status

CHU de Lille

Lille, , France

Site Status

CHU de Limoges

Limoges, , France

Site Status

Hôpital Lyon Sud

Lyon, , France

Site Status

Hôpital la Conception

Marseille, , France

Site Status

Clinique urologique CHU de NANTES

Nantes, , France

Site Status

University Hospital of Nimes

Nîmes, , France

Site Status

Hôpital de la Pitié-Salpêtrière

Paris, , France

Site Status

University of Rennes, Department of Urology

Rennes, , France

Site Status

CHU Rangueil

Toulouse, , France

Site Status

CHU Nancy

Vandœuvre-lès-Nancy, , France

Site Status

Klinikum Lippe

Detmold, , Germany

Site Status

Maastricht UMC+

Maastricht, , Netherlands

Site Status

Hospital de La Princesa

Madrid, , Spain

Site Status

Marqués de Valdecilla University Hospital

Santander, , Spain

Site Status

Addenbrooks Hospital

Cambridge, , United Kingdom

Site Status

Countries

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Belgium Czechia France Germany Netherlands Spain United Kingdom

Related Links

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Other Identifiers

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EAU-RF 2019-01

Identifier Type: -

Identifier Source: org_study_id

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