Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-01

Study Completion Date

2020-08-01

Brief Summary

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This study will try to provide a better understanding of the psychological, cognitive and electrophysiological factors that contribute to suicide in depressed patients.

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Detailed Description

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Objectives:

1. To investigate the ability of qEEG to suspect suicidal potential in patients diagnosed with major depression.
2. To test the ability of some psychological and cognitive elements in determining the likelihood of suicide in such patients.
3. To give an objective and more reliable method than traditional questionnaires to assess the seriousness of suicidal ideations in patients suffering from depression who usually don't reveal their actual intentions.

Conditions

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Suicide Major Depressive Disorder Quantitative EEG (qEEG)

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Study Group (MDD with SIs)

25 Egyptian patients diagnosed with major depression (with suicidal ideations)

Quantitative EEG

Intervention Type DIAGNOSTIC_TEST

1. Both groups will undergo evaluation of depression severity using Beck Depression Inventory Scale-II (Arabic Version)
2. Both groups will be assessed for psychological \& cognitive contributes respectively using:

A. Connor and Davidson Scale for resilience (Arabic Version) B. The scale of Islamic Religiosity Attitude (SIRA)
3. Both groups will do Quantitative EEG (qEEG) to detect electrical, functional and brain mapping changes {Using Neurovirtual BW III, Florida, USA)
4. The quantitative analysis of EEG will focus on the following functions:

Histogram, Topography, Spectrum Analysis, Spectral Differences, Propagation, Positional Diagram, Medium Amplitude, Ranges of Absolute Frequencies, Ranges of Relative Frequencies, CSA, Spectrum, and CSA Compressed.

Control group (MDD without SIs)

25 Egyptian patients diagnosed with major depression (without suicidal ideations)

Quantitative EEG

Intervention Type DIAGNOSTIC_TEST

1. Both groups will undergo evaluation of depression severity using Beck Depression Inventory Scale-II (Arabic Version)
2. Both groups will be assessed for psychological \& cognitive contributes respectively using:

A. Connor and Davidson Scale for resilience (Arabic Version) B. The scale of Islamic Religiosity Attitude (SIRA)
3. Both groups will do Quantitative EEG (qEEG) to detect electrical, functional and brain mapping changes {Using Neurovirtual BW III, Florida, USA)
4. The quantitative analysis of EEG will focus on the following functions:

Histogram, Topography, Spectrum Analysis, Spectral Differences, Propagation, Positional Diagram, Medium Amplitude, Ranges of Absolute Frequencies, Ranges of Relative Frequencies, CSA, Spectrum, and CSA Compressed.

Interventions

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Quantitative EEG

1. Both groups will undergo evaluation of depression severity using Beck Depression Inventory Scale-II (Arabic Version)
2. Both groups will be assessed for psychological \& cognitive contributes respectively using:

A. Connor and Davidson Scale for resilience (Arabic Version) B. The scale of Islamic Religiosity Attitude (SIRA)
3. Both groups will do Quantitative EEG (qEEG) to detect electrical, functional and brain mapping changes {Using Neurovirtual BW III, Florida, USA)
4. The quantitative analysis of EEG will focus on the following functions:

Histogram, Topography, Spectrum Analysis, Spectral Differences, Propagation, Positional Diagram, Medium Amplitude, Ranges of Absolute Frequencies, Ranges of Relative Frequencies, CSA, Spectrum, and CSA Compressed.

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Resilience scale (Carl & Davidson) Arabic version BDI (Beck Inventory II) Arabic version Suicide probability Scale (Arabic Version) Scale of Islamic Religiosity Attitude (SIRA)

Eligibility Criteria

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Inclusion Criteria

* Age between 16 and 65 years
* Both males and females will be enrolled
* Patients present with the clinical picture of Major depression according to DSM 5 criteria.

Exclusion Criteria

* Psychotic features associating depressive episode
* Bipolar depression
* The condition is due to another medical condition
* The condition is substance or medication-induced
* Intellectual disability
* Comorbid epilepsy

Minimum Eligible Age

16 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes