Normal Brain Imaging Database for Brain Disorder Studies

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-28

Study Completion Date

2025-12-31

Brief Summary

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Healthy volunteers will be recruited. All subjects will be tested a battery of neuropsychological tests, then undergo fluorodeoxyglucose-positron emission tomography (PET) and magnetic resonance imaging (MRI). During the PET and MRI, they will be stimulated with transcranial direct current stimulation (tDCS) for 15 minutes. A third of subjects will receive real tDCS on the left prefrontal cortex, a third on the right prefrontal cortex, and the other third will receive sham tDCS.

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Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Real Left DLPFC tDCS

Real tDCS on the left dorsolateral prefrontal cortex

Group Type ACTIVE_COMPARATOR

transcranial direct current stimulation

Intervention Type DEVICE

15 minute anodal stimulation 1.5mA

Sham tDCS

30sec ramp-up and 30sec ramp-down

Group Type SHAM_COMPARATOR

transcranial direct current stimulation

Intervention Type DEVICE

15 minute anodal stimulation 1.5mA

Real Right DLPFC tDCS

Real tDCS on the right dorsolateral prefrontal cortex

Group Type ACTIVE_COMPARATOR

transcranial direct current stimulation

Intervention Type DEVICE

15 minute anodal stimulation 1.5mA

Interventions

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transcranial direct current stimulation

15 minute anodal stimulation 1.5mA

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* N/A

Exclusion Criteria

* History of any neurological or psychiatric diseases;
* Abnormal MRI;
* metal implants or a cardiac pacemaker;
* Pregnant or breastfeeding women (female subjects of child bearing potential will be screened for pregnancy before MRI imaging).
* severe hypertension.
* cardiovascular disease.
* Family history of epilepsy.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes