Prevelance of Keratoconus

NCT ID: NCT04092426

Last Updated: 2019-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-01

Study Completion Date

2021-10-01

Brief Summary

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Keratoconus is a degenerative disease entity characterized by conical shape ectasia of the cornea. progressive conical deformation of the cornea leads to substantial astigmatism. Patients who are at an advanced stage of ectasia are often led to corneal transplant or other treatments, which essentially aim at correcting the refractive error and not in treating the ectasia. The top of the protruding cone that corneal configuration may be close to the visual axis or below and nasal of that. The disease manifests during adolescence, followed by slow progressive course, although it is possible to stabilize anytime. In 85% of cases both eyes are affected, but the severity of the attack can present significant asymmetry.

Detailed Description

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Often in keratoconus a positive family history is present. Prevelance of keratoconus varies greatly worldwide.The reported prevalence of keratoconus varies widely depending upon the geographic location, diagnostic criteria used, and the cohort of patients selected. Environmental factors may contribute to the wide variation in prevalence.

the Middle East have higher prevalence than locations with cooler climates and less sunshine

Conditions

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Keratoconus

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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patients with keratoconus

patients with keratoconus attending refractive surgery centers in Assiut will be subjected to the following :-

1. Full history and clinical evaluation.
2. collection of individual data ( residency , occupation , special habbit , chronic illness )
3. Analysis of results to assess prevelance of keratoconus and its distribution geographically in Assiut

opthalmologic examination

Intervention Type OTHER

opthalmologic examination : Refraction Best corrected visual acuity Intraocular pressure Slit lamp examination

Interventions

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opthalmologic examination

opthalmologic examination : Refraction Best corrected visual acuity Intraocular pressure Slit lamp examination

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. persons attending refractive surgery centers in Asssiut.
2. patients found to have keratoconus are included , based on history , clinical examination and corneal topography

Exclusion Criteria

1. patients not attending those refractive surgery centers.
2. patients attending these centers but not diagnosed to be keratoconus .
3. Pregnancy or breastfeeding
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Mariam hamdy

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Jonas JB, Nangia V, Matin A, Kulkarni M, Bhojwani K. Prevalence and associations of keratoconus in rural maharashtra in central India: the central India eye and medical study. Am J Ophthalmol. 2009 Nov;148(5):760-5. doi: 10.1016/j.ajo.2009.06.024. Epub 2009 Aug 11.

Reference Type BACKGROUND
PMID: 19674732 (View on PubMed)

Other Identifiers

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keratoconus in assiut

Identifier Type: -

Identifier Source: org_study_id

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