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Corneal Changes After Crosslinking in Keratoconus Patients Compared to the Untreated Fellow Eye

NCT ID: NCT02428166

Last Updated: 2017-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

66 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-02-28

Study Completion Date

2017-03-31

Brief Summary

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The purpose of this retrospective study is to assess corneal changes (keratometry, pachymetry) and change in visual acuity (VA) in keratoconus patients after unilateral crosslinking treatment compared to the untreated fellow eye. The corneal measurements obtained preoperatively and 2 to 14 months postoperatively using a Pentacam rotating scheimpflug camera are analyzed. Furthermore, pre-existing or actual ocular pathology or/and ocular surgeries as potential factors involved in treatment outcome are also evaluated.

Detailed Description

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Conditions

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Keratoconus

Keywords

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crosslinking keratoconus keratometry pachymetry pentacam

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Keratoconus patients after unilateral crosslinking treatment

Exclusion Criteria

* Morphological changes of the cornea caused be ocular infection or trauma (e.g. corneal scarring)
* Other pre-existing corneal surgery (e.g. corneal transplantation, implantation of intrastromal corneal ring segments)
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Heidelberg University

OTHER

Sponsor Role lead

Responsible Party

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Prof. Dr. med. Mike P. Holzer

Ophthalmologist, FEBO

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mike P Holzer, MD, FEBO

Role: PRINCIPAL_INVESTIGATOR

Department of ophthalmology, University of Heidelberg

Locations

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Department of ophthalmology, University of Heidelberg

Heidelberg, Baden-Wurttemberg, Germany

Site Status

Countries

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Germany

Other Identifiers

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S-004/2015

Identifier Type: -

Identifier Source: org_study_id