The Impact of Music on Nociceptive Processing

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

111 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-06-13

Study Completion Date

2023-05-23

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The investigators are studying the ways that different music may change pain perception

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Impact of Music Therapy on Nociceptive Processing

NCT03692247

Pain Chronic Pain

COMPLETED NA

Examining the Effects of Processed Music on Chronic Pain

NCT03083977

Pain

TERMINATED NA

Effect of Music on Pain and Anxiety in Chronic Pain Patients Undergoing Lumbar Interventional Procedures.

NCT04924244

Chronic Pain Anxiety

RECRUITING NA

Meaning in Music-Based Pain Modulation

NCT07036315

The Focus of the Study is Healthy Volunteers

RECRUITING NA

Central Neuromodulation of Pain Through Music in Healthy Subjects

NCT03914105

Pain

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

In this study, the investigators are comparing healthy individuals to HIV and Fibromyalgia patients. The investigators are measuring the differences in pain processing between subject groups in the presence and absence of different music and distraction conditions. The investigators will be using Quantitative Sensory Testing (QST) in order to induce varying pain conditions on the participants. The investigators will also have participants complete sets of psychosocial questionnaires. Patients with Fibromyalgia tend to have a higher pain sensitivity. Additionally, patients with an HIV diagnosis tend to be prescribed opioid medications. The investigators would like to find out if music can modulate pain, and in turn help reduce the amount of opioid medications those with a chronic pain diagnosis take.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pain, Acute Pain, Chronic Anxiety Anxiety Disorders Catastrophization Healthy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Each subject serves as their own control

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

music intervention

Healthy volunteers, and patients diagnosed with HIV or fibromyalgia will complete 4 rounds of QST testing; baseline + 3 music conditions to determine effect of music on pain sensitivity.

Group Type EXPERIMENTAL

music intervention

Intervention Type OTHER

The music intervention (Unwind), developed by the investigators collaborators at the Sync Project, is a machine learning protocol that generates specific sounds and phrases of music that are stitched into a music track in response to user-reported pain, anxiety and catastrophizing scales. Unwind is delivered via a web application on a smart phone.

Participants will also listen to white noise and their favorite music throughout the study session

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

music intervention

The music intervention (Unwind), developed by the investigators collaborators at the Sync Project, is a machine learning protocol that generates specific sounds and phrases of music that are stitched into a music track in response to user-reported pain, anxiety and catastrophizing scales. Unwind is delivered via a web application on a smart phone.

Participants will also listen to white noise and their favorite music throughout the study session

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Unwind Favorite Music White Noise

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* aged \>18 years
* able to speak and understand English
* willingness to undergo psychophysical and psychosocial testing.

* aged \>18 years
* have a diagnosis of fibromyalgia with concurrent chronic pain for \> 6 months, and meet the Wolfe et al 2011 research criteria for fibromyalgia
* have an average self-reported pain score of 4/10 or greater
* willing to undergo psychophysical and psychosocial testing
* able to speak and understand English.

Exclusion Criteria

* diagnosed hearing loss
* diagnosis of chronic pain/neuropathy
* history of chronic opioid use (having an opioid prescription \>30 days).

--diagnosed hearing loss.

HIV Patients with chronic pain: N=70

* aged \>18- years
* have a diagnosis of HIV infection
* have had chronic pain with onset \> 6 months
* have an average self-reported pain score of 4/10 or greater
* willing to undergo psychophysical and psychosocial testing
* able speak and understand English.

--diagnosed hearing loss.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes