Ropivacaine/Dexamethasone and 10% Lignocaine Injection in GPN Block for Intractable Cancer Pain

NCT ID: NCT04085120

Last Updated: 2019-09-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-08-23

Study Completion Date

2020-02-28

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study will compare the efficacy and safety of Ropivacaine/dexamethasone vs 10% lignocaine injection in distal glossopharyngeal nerve block for intractable cancer pain

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cancer, Oropharynx Pain, Intractable Cancer Pain

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Ropivacaine/dexamethasone group

3ml of 0.75% ropivacaine and 1ml of 4mg/l dexamethasone will be injected.

Group Type EXPERIMENTAL

0.75 % Ropivacaine/ 4mg/mL dexamethasone injection

Intervention Type PROCEDURE

Distal glossopharyngeal nerve in the neck will be blocked by using 0.75 % Ropivacaine/ 4mg/mL dexamethasone injection

10% lignocaine injection group

4 ml of 10% lignocaine

Group Type EXPERIMENTAL

10% lignocaine injection

Intervention Type PROCEDURE

Distal glossopharyngeal nerve in the neck will be blocked by using 10% lignocaine injection

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

0.75 % Ropivacaine/ 4mg/mL dexamethasone injection

Distal glossopharyngeal nerve in the neck will be blocked by using 0.75 % Ropivacaine/ 4mg/mL dexamethasone injection

Intervention Type PROCEDURE

10% lignocaine injection

Distal glossopharyngeal nerve in the neck will be blocked by using 10% lignocaine injection

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients with proven carcinoma of the oropharynx and supraglottic larynx with estimated survival of 3 months or more.
* Pain lasting for at least 2 weeks with an average intensity of 5 or more on an 11-point numeric rating scale (NRS) refractory to a combination strong opioids and NSAIDS

Exclusion Criteria

1. Local infection or skin ulceration at the puncture site
2. Local anaesthetic allergy
3. Psychiatric illness that affected cooperation.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

All India Institute of Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Dr.Dinesh Manoharan

Senior Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Dinesh Manoharan, MD

Role: PRINCIPAL_INVESTIGATOR

All India Institute of Medical Sciences

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

All India Institute of Medical Sciences

New Delhi, National Capital Territory of Delhi, India

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

India

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Dinesh Manoharan, MD

Role: CONTACT

918447857079

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

DINESH MANOHARAN

Role: primary

8447857079

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

IEC-402/07.06.2019, RP-34/2019

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Mixed Local for Sciatic Block
NCT06671028 NOT_YET_RECRUITING NA