Electronic Early Notification of Sepsis in Hospitalized Ward Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

65250 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-01

Study Completion Date

2022-11-30

Brief Summary

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Screening for sepsis has been recommended by the Surviving Sepsis Campaign Clinical Practice Guidelines to facilitate early identification and early management of sepsis. However, the optimal tool remains unknown.The objective of this trial is to examine the effect of an electronic sepsis alert tool on reducing hospital mortailty in patients admitted to medical-surgical-oncology wards.

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Detailed Description

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The study aims to examine the effect of screening for sepsis using an electronic sepsis alert versus no alert in hospitalized patients admitted to wards using an active sepsis alert system compared with wards with no active (masked) sepsis alert system on hospital mortality by day 90.

The wards will be randomized in a stepped-wedge cluster fashion.

Conditions

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Sepsis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Stepped-wedge Cluster Randomized Controlled Trial

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

The electronic alert will be masked on the control wards.

Study Groups

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Experimental wards

Active sepsis e-alert

Group Type EXPERIMENTAL

sepsis e-alert

Intervention Type OTHER

At 2-each month interval, the e-alert will be activated in five new randomly selected wards, until all wards eventually will have active alert

Contol wards

Masked sepsis e-alert.

The wards will have masked sepsis e-alert.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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sepsis e-alert

At 2-each month interval, the e-alert will be activated in five new randomly selected wards, until all wards eventually will have active alert

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1\. Inpatient wards, defined as wards used to manage inpatients, in the five Ministry of National Guard Health Affairs (MNGHA) hospitals, Kingdom of Saudi Arabia

1. Aged 14 years or older
2. Checked in as inpatient status to one of the study ward

Exclusion Criteria

1. Cardiology, transplant, pediatric, obstetric wards
2. Intensive Care Units and Emergency Department
3. Operating rooms
4. Outpatients
5. Day care wards, endoscopy, outpatient procedure areas, hemodialysis units.

1\. No commitment for full life support on the time of arrival to the study ward

Minimum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No