Repository for Sepsis and Postresuscitation Samples

NCT ID: NCT01670383

Last Updated: 2023-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-07-31

Study Completion Date

2028-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The objective of this study is to find a new therapeutic strategy by investigating the serial serum samples of patients with sepsis or postresuscitation state.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cardiac Arrest Sepsis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Postresuscitation group

Adults (age over 16 years old) who have survived from nontraumatic cardiac arrest and admitted to ICU.

No interventions assigned to this group

Sepsis group

Adults (age over 16 years old) who satisfy the sepsis criteria (SIRS\>=2 and infection is suspected for a cause) and admitted to the ICU.

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age over 16 years old
* Admitted to ICU
* Diagnosed as having sepsis or as postresuscitation status
* Definition of sepsis: 2 or more SIRS criteria + infection is suspected
* Definition of postresuscitation status: Survived from non-traumatic cardiac arrest

Exclusion Criteria

* refusal to participate
* DNAR status
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Gil Joon Suh

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Gil Joon Suh, Professor

Role: STUDY_DIRECTOR

Seoul National University Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Seoul National University Hospital

Seoul, , South Korea

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

South Korea

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Kyung Su Kim, MD, PhD

Role: CONTACT

82-10-8033-1127

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Kyung Su Kim, MD, PhD

Role: primary

References

Explore related publications, articles, or registry entries linked to this study.

Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001 Jul;29(7):1303-10. doi: 10.1097/00003246-200107000-00002.

Reference Type BACKGROUND
PMID: 11445675 (View on PubMed)

Dombrovskiy VY, Martin AA, Sunderram J, Paz HL. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med. 2007 May;35(5):1244-50. doi: 10.1097/01.CCM.0000261890.41311.E9.

Reference Type BACKGROUND
PMID: 17414736 (View on PubMed)

Cohen J. The immunopathogenesis of sepsis. Nature. 2002 Dec 19-26;420(6917):885-91. doi: 10.1038/nature01326.

Reference Type BACKGROUND
PMID: 12490963 (View on PubMed)

Schneider A, Bottiger BW, Popp E. Cerebral resuscitation after cardiocirculatory arrest. Anesth Analg. 2009 Mar;108(3):971-9. doi: 10.1213/ane.0b013e318193ca99.

Reference Type BACKGROUND
PMID: 19224811 (View on PubMed)

Kim KS, Suh GJ, Jin M, Kwon WY, Jung YS, Kim T, Kim YT, Kim H, Park H. SECRETED TRYPTOPHANYL-tRNA SYNTHETASE 1 IS A PROGNOSTIC MARKER IN SEPSIS PATIENTS WITHOUT MONOCYTOPENIA. Shock. 2024 Jan 1;61(1):55-60. doi: 10.1097/SHK.0000000000002259. Epub 2023 Oct 20.

Reference Type DERIVED
PMID: 37878497 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

SNUHEM-Repository-12-0001

Identifier Type: -

Identifier Source: org_study_id