Donor Gender Effect on Graft Function in Adult Egyptian Patients Undergoing Living Donor Liver Transplant

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

342 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-08-15

Study Completion Date

2021-06-20

Brief Summary

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Liver transplantation (LT) represents the gold-standard therapy for the treatment in case of dreadful liver pathologies . It is thus a main concern to optimize the results in terms of post-LT survivals. The effect of gender match on post-transplant outcome is still debatable. Hormonal , and size difference between female and male may be proposed to affect the post transplant outcome . The aim of this study is to evaluate the effect of donor-recipient gender mismatch on survival rates

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Detailed Description

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Conditions

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Donor to Recipient Gender Mismatch in LDLT

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Matched group

Same sex of both donor and recipient

non interventional

Intervention Type OTHER

non interventional study

Mismatched group

Sex mismatch between donor and recipient, subgroups might be added

non interventional

Intervention Type OTHER

non interventional study

Interventions

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non interventional

non interventional study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adult Egyptian Patients \>18 years.

Exclusion Criteria

* Patient refusal.
* Patients who underwent re-transplantation before discharge from the ICU after the first liver transplant.
* Intraoperative cardiac arrest or immediately postoperative cardiac arrest within the first 6 hours postoperative.
* Massive blood loss.
* Pre-existing renal failure requiring hemodialysis or continuous hemofiltration.
* Pregnancy.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No