The Role of Left Prefrontal Transcranial Magnetic Stimulation in Episodic Migraine Prophylaxis
NCT ID: NCT04031781
Last Updated: 2019-07-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
33 participants
INTERVENTIONAL
2013-05-01
2015-02-01
Brief Summary
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A group received 5 rTMS sessions, delivered over one week. Each rTMS session consisted of a single train of 900 total pulses over 3 minutes duration given at 5-Hz frequency and 100% motor threshold intensity and the placebo group received rTMS with the same stimulation frequency at a fixed intensity of 50% of the machine output
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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Receiving repetitive transcranial magnetic stimulation (rTMS)
This group received 5 rTMS sessions, delivered over one week over the left dorsolateral prefrontal cortex (LDLPFC ) at 5-Hz frequency and 100% motor threshold intensity.
repetitive transcranial magnetic stimulation (rTMS) 100% motor threshold
Each rTMS session consisted of a single train of 900 total pulses over 3 minutes duration.
Group receiving placebo rTMS
This group received Placebo rTMS was given with the same stimulation frequency at a fixed intensity of 50% of the machine output
repetitive transcranial magnetic stimulation (rTMS) 50% motor threshold
Each rTMS session consisted of a single train of 900 total pulses over 3 minutes duration.
Interventions
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repetitive transcranial magnetic stimulation (rTMS) 100% motor threshold
Each rTMS session consisted of a single train of 900 total pulses over 3 minutes duration.
repetitive transcranial magnetic stimulation (rTMS) 50% motor threshold
Each rTMS session consisted of a single train of 900 total pulses over 3 minutes duration.
Eligibility Criteria
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Inclusion Criteria
* With a headache frequency of 4-14 per month for the last six months
* Patients who had either an unsatisfactory response, declined or were intolerant to at least two prophylactic medications.
Exclusion Criteria
* Other chronic pain disorders
* Severe depression (Beck Depression Inventory of 30 or more)
* Other significant neurologic or psychiatric diagnosis including substance misuse
* Metal implants in the head
* Pregnant or breastfeeding ladies
* Prior experience with TMS
16 Years
ALL
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Tamer Emara
Assistant professor of neurology
Other Identifiers
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FMASU 1171/2012
Identifier Type: -
Identifier Source: org_study_id
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