Efficacy of rTMS in the Treatment of Patients With Migraine

NCT ID: NCT00316979

Last Updated: 2010-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Migraine is a condition thought to be related to cortical hyperexcitability. Repetitive transcranial magnetic stimulation (rTMS) can modulate the cortical excitability by means of long-term potentiation or long-term depression. This study will will test the safety and efficacy of rTMS in the treatment of patients with Migraine.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Migraine

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Repetitive Transcranial Magnetic Stimulation (rTMS)

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age of 18-65 years
* Diagnosed as migraine (with or without aura)
* More than 4 attacks per month for at least 3 months prior to study
* No preventive medication used
* Must be able to sign permit

Exclusion Criteria

* History of seizure or family history of seizures
* Women in pregnancy or breast-feeding
* Patient with medication overuse
* Patient with other medical, psychologic, or surgical illness
* Patient under preventive medications
* Prior rTMS examination one month within
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

National Science and Technology Council, Taiwan

OTHER_GOV

Sponsor Role collaborator

Taipei Veterans General Hospital, Taiwan

OTHER_GOV

Sponsor Role lead

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Shuu-Jiun Wang, MD

Role: PRINCIPAL_INVESTIGATOR

Headache Center, Taipei Veterans General Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Headache Center, Teipei Veterans General Hospital

Taipei, , Taiwan

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Taiwan

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Shuu-Jiun Wang, MD

Role: CONTACT

+886-2-28712121 ext. 2425

Kuan-Lin Lai, MD

Role: CONTACT

+886-2-28712121 ext. 3185

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Shuu-Jiun Wang, MD

Role: primary

+886-2-28712121 ext. 2425

Jong-Ling Fuh, MD

Role: backup

+886-2-28712121 ext. 3256

References

Explore related publications, articles, or registry entries linked to this study.

Brighina F, Piazza A, Vitello G, Aloisio A, Palermo A, Daniele O, Fierro B. rTMS of the prefrontal cortex in the treatment of chronic migraine: a pilot study. J Neurol Sci. 2004 Dec 15;227(1):67-71. doi: 10.1016/j.jns.2004.08.008.

Reference Type BACKGROUND
PMID: 15546593 (View on PubMed)

Lorenz J, Minoshima S, Casey KL. Keeping pain out of mind: the role of the dorsolateral prefrontal cortex in pain modulation. Brain. 2003 May;126(Pt 5):1079-91. doi: 10.1093/brain/awg102.

Reference Type BACKGROUND
PMID: 12690048 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

rTMS_Migraine_VGHTPE

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.