Study of Nutrition and Activity in Kids

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

201 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-06-29

Study Completion Date

2021-02-28

Brief Summary

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While a substantial body of research suggests that RRV is related to obesity, there is very little research on factors that contribute to the RRV of food, particularly how patterns of eating can increase or decrease the motivation to eat specific foods. Previous work has demonstrated that a subset of individuals with obesity show increases in RRV of food after repeated consumption of large portions of high energy density (HED) snack foods, which has been conceptualized as sensitization. Preliminary data suggest that sensitization of the RRV of HED food is a predictor of weight gain over time. However, more work needs to be done to address this relationship using a planned, prospective study design, using adolescent research subjects, and examining potential moderators of this relationship.

The purpose of this study is to identify risk and protective factors to excess zBMI change in adolescents over time. Aim 1 was to measure the relative reinforcing value (RRV) of a preferred HED and low energy density (LED) snack food before and after 2-weeks of daily exposure. Aim 2 was to assess the RRV of exercise and sedentary activity. Hypotheses include 1) sensitization to HED food will be associated with greater zBMI at the time of testing as well as greater zBMI change over time 2) sensitization to LED food will be associated with lower zBMI at the time of testing in adolescents and less zBMI change over time. 3) Greater RRV of exercise will be protective against zBMI increases over time.

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Detailed Description

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Conditions

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Obesity, Adolescent Adolescent Behavior

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Reinforcing value of HED and LED foods in response to snack food monotony

Each child will be asked to eat two different snack foods over the course of two weeks each. The RRV of that food (vs alternative reinforcer) will be tested and baseline and post exposure. Increases in RRv for food after monotony will be considered sensitization to that food. All children will be followed to observe weight change over time for 2 years each.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* between 12-14yoa (male and female)
* zBMI: -1.5 to +2.0 (\*determined by Height/weight measurement at Visit 1)
* neutral or higher liking of the study foods
* Willingness to complete 9 study visits over 2 years.

Exclusion Criteria

* -metabolic or endocrine disorder
* use of medications known to effect appetite (Ritalin, Adderall, Concerta, Wellbutrin, Prednisone, etc)
* Unwilling to complete the study visits
* allergy to study foods
* dislike of study foods (\*determined via Preference for Study foods forms at Visit 1)
* parent report that child reads below 4th grade reading level
* parent report that child cannot complete light physical activity without assistance

Minimum Eligible Age

12 Years

Maximum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes