Effect of Dexmedetomidine on the Inflammatory Response After One-lung Ventilation
NCT ID: NCT04007341
Last Updated: 2019-07-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2018-07-29
2019-01-18
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Saline group
Patients in the saline group were infused with an identical volume of normal saline.
No interventions assigned to this group
Dexmedetomidine group
Patients in the dexmedetomidine group were infused with a loading dose of dexmedetomidine (1.0 mcg/kg over 10 min) and were thereafter infused at a rate of 0.5 mg/kg/h.
Dexmedetomidine
The study drug for each group was administered from the time immediately after induction of anesthesia until the end of the surgery.
Interventions
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Dexmedetomidine
The study drug for each group was administered from the time immediately after induction of anesthesia until the end of the surgery.
Eligibility Criteria
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Inclusion Criteria
* 20 \< age \< 75
* American Society of Anesthesiologists (ASA) classification I\~II
Exclusion Criteria
* steroid administration within 1 month
* hematologic / autoimmune disease
* congestive heart failure (NYHA class III\~IV) or significant arrhythmia
* severe obstructive / restrictive pulmonary disease
* previous history of thoracic surgery
20 Years
75 Years
ALL
No
Sponsors
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Seoul St. Mary's Hospital
OTHER
Responsible Party
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Wonjung Hwang
Assistant professor
Locations
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Seoul St.Mary's Hospital
Seoul, , South Korea
Countries
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Other Identifiers
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KC16MISI0042
Identifier Type: -
Identifier Source: org_study_id
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