Study of Quality Perception on Music in New Cochlear Implanted Subjects Using or Not a Fine Structure Strategy

NCT ID: NCT03993899

Last Updated: 2020-01-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

19 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-07-01

Study Completion Date

2020-01-07

Brief Summary

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Main objective:

Show the superiority of Fine Structure (FS4) strategy compared to Continuous Interleaved Sampling (HDCIS) strategy on the qualitative preference for the listening of musical pieces.

Secondary objectives

* Show the superiority of FS4 strategy compared to the HDCIS strategy on the perception of musical elements (contour test).
* Analyze the link between the results of musical perception tests and the subjective preference of musical listening.
* Show the non inferiority of FS4 strategy compared to the HDCIS strategy on the perception of speech elements.
* Analyze the link between the results of musical perception tests and the results of the perception of speech elements.
* Analyze the qualitative multidimensional perception with HDCIS and FS4

Detailed Description

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Introduction:

At present, most people with modern cochlear implant systems can understand speech using the device alone, at least under favorable listening conditions.

In recent years, research has increasing focussed on how implant users perceive sounds other than speech. In particular, music perception is of interest.

A review of the literature on musical perception with traditional implants, coding only the temporal envelope \[McDermott 2004\], revealed the following elements:

* On average, implant users perceive the rhythm approximately as well as listeners with normal hearing
* With technically sophisticated multi-channel sound processors, melody recognition, especially without rhythmic or verbal cues, is poor.
* The perception of timbre, especially the sounds of musical instruments, is generally unsatisfactory.
* Implant users tend to rate the quality of musical sounds as less enjoyable than listeners with normal hearing And studies show that the fine structure of sound is the main vector of information for music and the location of sounds. \[Smith et al. 2002\] It therefore seems necessary to focus on the contribution of the coding of the fine temporal structure of sound to the cochlear implant.

Main objective:

Show the superiority of FS4 strategy compared to HDCIS strategy on the qualitative preference for the listening of musical pieces.

Secondary objectives:

* Show the superiority of FS4 strategy compared to the HDCIS strategy on the perception of musical elements (contour test).
* Analyze the link between the results of musical perception tests and the subjective preference of musical listening.
* Show the non inferiority of FS4 strategy compared to the HDCIS strategy on the perception of speech elements.
* Analyze the link between the results of musical perception tests and the results of the perception of speech elements.
* Analyze the qualitative multidimensional perception with HDCIS and FS4

Plan of the study:

It is a prospective open monocentric randomized crossover study: measures will be done on the patient at 15 days and 30 days post-activation.

Conditions

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Sensorineural Hearing Loss, Bilateral

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

two arms A and B:

Arm A: patient's fitting with strategy FS4 --\> 15 days use --\> tests and patient's fitting with strategy HDCIS --\> 15 days use --\> tests

Arm B: patient's fitting with strategy HDCIS --\> 15 days use --\> tests and patient's fitting with strategy FS4 --\> 15 days use --\> tests
Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Investigators
Double blind study: the patient and the investigator don't know the strategy

Study Groups

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Cochlear implant (CI) with FineHearing Strategy then HDCIS

cochlear implant with FineHearing strategy first during 15 days then with HDCIS strategy during 15 days

Group Type ACTIVE_COMPARATOR

FineHearing strategy or HDCIS strategy

Intervention Type DEVICE

Cochlear implant with FineHearing strategy or HDCIS strategy

CI with HDCIS Strategy then FS4

cochlear implant with HDCIS strategy first during 15 days then with FS4 strategy during 15 days

Group Type ACTIVE_COMPARATOR

FineHearing strategy or HDCIS strategy

Intervention Type DEVICE

Cochlear implant with FineHearing strategy or HDCIS strategy

Interventions

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FineHearing strategy or HDCIS strategy

Cochlear implant with FineHearing strategy or HDCIS strategy

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult patient (≥ 18 years old) speaking French
* Patient who fulfils the criteria for cochlear implantation

Exclusion Criteria

\- Retro-cochlear pathology: auditory neuropathy, vestibular schwannoma
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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MED-EL Elektromedizinische Geräte GesmbH

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Benoit Godey, Pr

Role: PRINCIPAL_INVESTIGATOR

Rennes University Hospital

Locations

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CHU Rennes

Rennes, , France

Site Status

Countries

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France

Other Identifiers

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MED_EL_FS_music_Rennes_study

Identifier Type: -

Identifier Source: org_study_id

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