Effects of Pulses on Loudness

NCT ID: NCT04010721

Last Updated: 2021-10-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-10

Study Completion Date

2020-08-25

Brief Summary

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The aim of this study is to investigate the effect of varying additional factors on loudness summation in Neuro Zti Cochlear Implant users.

Detailed Description

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Primary objective:

\- To assess the effect of the number and spatial distribution of active electrodes on the stimulation charge required to achieve the loudness associated with C and T levels (Experiment 2).

Secondary objectives:

* To assess how loudness is affected by changes in electrical charge of individual pulses made by adjusting the pulse amplitude versus adjusting pulse duration (Experiment 1).
* To assess how loudness elicited by a train of pulses is affected by the duration of that pulse train (Experiment 3).

Experiment 1:

The test will investigate the effect of loudness on changes in electrical charge of individual pulses, made by separately adjusting pulse amplitude or pulse width. The electrical charge required to elicit different loudness ("just-audible", "soft", "medium", "comfortable", "loud but comfortable") either when increasing the amplitude or the duration of the pulses.

Experiment 2:

The test will investigate the effect of the number of stimulating electrodes and their distribution within the cochlea on the stimulation levels required to achieve T-levels and C-levels and to elicit different loudness ("just-audible", "soft", "medium", "comfortable", "loud but comfortable").

Experiment 3:

The test will investigate the effect on loudness of trains of pulses elicited by modifications to the duration of those trains, when operating around T and C levels. Stimulation durations ranging from 10 to 600 ms will be tested. Pulse trains will be presented to either one or several electrodes to elicit different loudness ("just-audible", "soft", "medium", "comfortable", "loud but comfortable").

Conditions

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Hearing Loss, Cochlear

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Experimental : experiment 1,2 and 3

One user included participates all experiments:

* Visit 1 : experiment 1
* Visit 2 : experiment 2
* Visit 3 : experiment 3

Group Type OTHER

Experiment 1

Intervention Type DEVICE

Stimulation of one electrode at a time

Experiment 2:

Intervention Type DEVICE

Stimulation in groups of 4, 8 and 12 electrodes

Experiment 3

Intervention Type DEVICE

Stimulation total duration from 10 to 600 ms

Interventions

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Experiment 1

Stimulation of one electrode at a time

Intervention Type DEVICE

Experiment 2:

Stimulation in groups of 4, 8 and 12 electrodes

Intervention Type DEVICE

Experiment 3

Stimulation total duration from 10 to 600 ms

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Neuro One or Neuro 2 user
* Unilateral or bilateral recipient
* 12 months CI experience to allow for acclimatization to the CI sound processing and pathological changes that could alter the electrode - tissue interface and therefore T- \& C-levels.
* Having at least 7 step sizes on three electrodes in their current clinical map (for experimentation 1).
* Able and willing to provide reliable threshold and comfort level judgements

Exclusion Criteria

* Medical conditions that contraindicate the study tests (e.g. tinnitus, dizziness)
* Unrealistic expectations from the candidate regarding the possible benefits, risks, and limitations that are inherent to the device
* Unwillingness or inability of the candidate to comply with all investigational requirements
* Vulnerable population
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Oticon Medical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Christophe VINCENT

Role: PRINCIPAL_INVESTIGATOR

CHRU LILLE

Locations

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CHU Lille

Lille, , France

Site Status

Countries

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France

Other Identifiers

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PIC-19

Identifier Type: -

Identifier Source: org_study_id