Multimodal Retinal Imaging of Cerebrovascular Stroke

NCT ID: NCT03964610

Last Updated: 2022-03-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

62 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-11-15

Study Completion Date

2022-02-15

Brief Summary

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The hypothesis is that in patients with stroke, abnormalities of retinal microvascularization shown on color fundus photography and the depletion of retinal capillary density evaluated by OCT-A are markers of acute impairment of microcirculation of the central nervous system and are correlated with lesions on brain imaging.

Patients hospitalized for stroke MRI-confirmed, will be included. An ophthalmologic assessment including color fundus photography (CFP) and OCT-A will be carried out after stabilization and at 3 months follow-up. Outcomes assessor will be blinded.

Detailed Description

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Conditions

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Stroke Cerebrovascular Accidents

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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color fundus photography (CFP) and OCT-A

Included patients will have an ophthalmologic assessment (OCT-A and CPF) after stabilization and at 3 months follow-up.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Acute ischemic stroke
* With cerebral microangiopathy (defined by a SVD score \> 1)

Exclusion Criteria

* Acute hemorrhagic stroke
* Anophthalmia
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondation Ophtalmologique Adolphe de Rothschild

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Fondation A de Rothschild

Paris, , France

Site Status

Countries

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France

Other Identifiers

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RHE_2019_10

Identifier Type: -

Identifier Source: org_study_id

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