Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
1200 participants
INTERVENTIONAL
2019-10-01
2024-10-15
Brief Summary
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The use of an adaptive optics system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many retinal microstructures: photoreceptors, vessels, bundles of nerve fibers.
Recently, the development of the coupling of the two main imaging techniques, the Adaptive Optics Ophthalmoscope with Optical Coherence Tomography, enables unparalleled three-dimensional in vivo cell-scale imaging, while remaining comfortable for the patients.
The purpose of this project is to evaluate the performance of this system for imaging micrometric retinal structures.
Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
OTHER
NONE
Study Groups
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Bimodal and coaxial high resolution imaging of the retina
Optical coherence tomography and Scanning laser ophthalmoscope system using adaptive optics (AO-SLO-OCT)
Bimodal high resolution imaging of the retina
The protocol consists of performing an Optical coherence tomography and Scanning laser ophthalmoscope system using adaptive optics (AO-SLO-OCT).The participant is asked to put his forehead against the temple supports and his chin on a chin rest. The subject will be asked to fix a test pattern in the form of a cross. The pattern is positioned according to the desired eccentricity with respect to the fovea. The actual acquisition lasts a few seconds, possibly repeated to cover the field of the desired eye. The acquisition protocol depends on the subjects, their pathology and the system used; the area examined will be modified on a case by case basis. The total duration of each exam can be estimated at less than half an hour, with frequent breaks.
Interventions
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Bimodal high resolution imaging of the retina
The protocol consists of performing an Optical coherence tomography and Scanning laser ophthalmoscope system using adaptive optics (AO-SLO-OCT).The participant is asked to put his forehead against the temple supports and his chin on a chin rest. The subject will be asked to fix a test pattern in the form of a cross. The pattern is positioned according to the desired eccentricity with respect to the fovea. The actual acquisition lasts a few seconds, possibly repeated to cover the field of the desired eye. The acquisition protocol depends on the subjects, their pathology and the system used; the area examined will be modified on a case by case basis. The total duration of each exam can be estimated at less than half an hour, with frequent breaks.
Eligibility Criteria
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Inclusion Criteria
* Patient with a pathology affecting the eye or healthy volunteer
* Participant who signed the consent
* Beneficiaries of the health insurance
Exclusion Criteria
* Patients who have just received a photodynamic therapy treatment
* Patients taking drugs with photosensitivity as a side effect.
* Persons with pacemakers or other implanted electronic medical device
* Patients with viral conjunctivitis or any other infectious disease.
* Patients with skin lesions on the neck or forehead
* Patients at high risk of damage from optical radiation, such as aphakic patients, or patients with decreased sensitivity to light due to fundus disease.
* Participant unable to be followed throughout the study
* Advanced cataract or severe opacities in the anterior segment of the eye.
18 Years
ALL
Yes
Sponsors
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Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
OTHER
Responsible Party
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Principal Investigators
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Michel PAQUES
Role: PRINCIPAL_INVESTIGATOR
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Locations
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Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Paris, , France
Countries
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Central Contacts
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Facility Contacts
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Michel Paques, puph
Role: primary
Other Identifiers
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2016-A00704-47
Identifier Type: OTHER
Identifier Source: secondary_id
P16-02
Identifier Type: -
Identifier Source: org_study_id