A Dispensing Comparison of a Test Daily 1 Day Lens Against a Control 1 Day Lens.

NCT ID: NCT03951610

Last Updated: 2020-06-18

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-21

Study Completion Date

2019-06-04

Brief Summary

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The purpose of this study is to compare the dispensing performance of somofilcon A test 1 day contact lens against somofilcon A control 1 day contact lens.

Detailed Description

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The purpose of this study is to evaluate the clinical performance of a silicone-hydrogel test contact lens compared to the commercially available silicone-hydrogel (control) contact lens when worn over one week for each lens type in a randomized, bilateral, cross-over, dispensing study on a daily disposable basis.

Conditions

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Myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

This will be a, prospective, double-masked, randomized, bilateral, 1 week cross-over, dispensing study
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators
Double (participant and investigator)

Study Groups

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Test lens

Subjects wearing the test lens for one week, either randomized as the first or second pair.

Group Type EXPERIMENTAL

Test lens

Intervention Type DEVICE

contact lens

Control lens

Intervention Type DEVICE

contact lens

Control lens

Subjects wearing the control lens for one week, either randomized as the first or second pair.

Group Type ACTIVE_COMPARATOR

Test lens

Intervention Type DEVICE

contact lens

Control lens

Intervention Type DEVICE

contact lens

Interventions

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Test lens

contact lens

Intervention Type DEVICE

Control lens

contact lens

Intervention Type DEVICE

Other Intervention Names

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Invigor I DD lens Somofilcon A 1 day Test Clariti 1-day Somofilcon A 1 day control

Eligibility Criteria

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Inclusion Criteria

* Has had a self-reported oculo-visual examination in the last two years.
* Is at least 18 years of age and has full legal capacity to volunteer.
* Has read and understood the information consent letter.
* Is willing and able to follow instructions and maintain the appointment schedule.
* Is correctable to a visual acuity of 20/40 or better (in each eye) with their habitual vision correction or 20/20 best-corrected.
* Currently wears soft contact lenses (average wearing of 8 hours/day and 5 days/week) without the need of using rewetting drops
* Requires spectacle lens spherical powers between -1.00 to -5.75 diopters sphere (0.25D steps).
* Has no more than 0.75 diopters of refractive astigmatism.
* Has clear corneas and no active ocular disease.
* Has not worn lenses for at least 12 hours before the examination.
* Has a usable pair of spectacle lenses if required for transportation to the site for the initial visit

Exclusion Criteria

* Is presently participating in any other clinical or research study including eye related clinical or research study.
* Has never worn contact lenses before.
* Has any systemic disease affecting ocular health.
* Has any active ocular pathology or severe insufficiency of lacrimal secretion (moderate to severe dry eyes) that would affect the wearing of contact lenses.
* Is using any systemic or topical medications that will affect a study outcome variable, and/or ocular health.
* Has any known sensitivity to fluorescein dye or products to be used in the study.
* Has persistent, clinically significant corneal or conjunctival staining using sodium fluorescein dye.
* Has any clinically significant lid or conjunctival abnormalities, active neovascularization or any central corneal scars.
* Is aphakic.
* Has undergone corneal refractive surgery.
* Is pregnant, lactating, or planning a pregnancy at the time of enrollment (by verbal confirmation at the screening visit).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University Eye Center at Ketchum Health

Anaheim, California, United States

Site Status

Clinical Optics Research Lab (CORL) Indiana University School of Optometry, Indiana University

Bloomington, Indiana, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CV-19-01

Identifier Type: -

Identifier Source: org_study_id

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