Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens

NCT ID: NCT06046209

Last Updated: 2024-12-12

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-28

Study Completion Date

2023-11-22

Brief Summary

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The purpose of this study was to compare subjective ratings of lens handling at insertion for a monthly replacement lens versus a daily disposable lens in habitual soft lens wearers.

Detailed Description

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This was a non-dispensing, randomized, double-masked, crossover study. Participants wore 2 different contact lenses bilaterally over 4 study visits, all conducted on the same day. Estimated duration of involvement for each participant was 4 hours.

Conditions

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Myopia

Keywords

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Refractive Errors Eye Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Control Lens, then Test Lens

Participants wore the Control Lens for 90 minutes, then the Test Lens for 90 minutes.

Group Type EXPERIMENTAL

Control Lens

Intervention Type DEVICE

Daily disposable contact lens for 90 minutes

Test Lens

Intervention Type DEVICE

Monthly replacement contact lens for 90 minutes

Test Lens, then Control Lens

Participants wore the Test Lens for 90 minutes, then the Control Lens for 90 minutes.

Group Type EXPERIMENTAL

Control Lens

Intervention Type DEVICE

Daily disposable contact lens for 90 minutes

Test Lens

Intervention Type DEVICE

Monthly replacement contact lens for 90 minutes

Interventions

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Control Lens

Daily disposable contact lens for 90 minutes

Intervention Type DEVICE

Test Lens

Monthly replacement contact lens for 90 minutes

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Were 17 to 40 years of age and have full legal capacity to volunteer;
2. Had read and signed an information consent letter;
3. Were willing and able to follow instructions and maintain the appointment schedule;
4. Were habitual daily wearers of spherical single vision soft contact lenses to correct for distance vision in each eye
5. Were correctable to a visual acuity of 20/20 or better (in each eye) with sphero-cylindrical subjective refraction;
6. Had an astigmatism of ≤ 0.75DC in subjective refraction;
7. Could be fit with the study contact lenses with a power between -1.00 and -6.00DS; this translates to best corrected vision sphere refraction that vertexes to a CL power between -1.00 and -6.00 (inclusive) at screening visit.
8. Demonstrated an acceptable fit with the study lenses.

Exclusion Criteria

1. Had taken part in another clinical research study within the last 14 days;
2. Were currently habitual wearers of toric, multifocal or monovision lenses.
3. Had worn any rigid contact lenses in the past 6 months
4. Were an extended lens wearer (i.e., sleeping with their lenses)
5. Had a difference of ≥1.5 D in best vision sphere subjective refraction between eyes;
6. Had amblyopia and/or distance strabismus/binocular vision problem;
7. Had any known active ocular disease, allergies and/or infection;
8. Had a systemic condition that in the opinion of the investigator may affect a study outcome variable;
9. Were using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable;
10. Had a known sensitivity to the diagnostic pharmaceuticals to be used in the study;
11. Had undergone refractive error surgery or intraocular surgery;
12. Were a member of CORE directly involved in the study.
Minimum Eligible Age

17 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre for Ocular Research & Education, Canada

OTHER

Sponsor Role collaborator

CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Lyndon Jones, PhD FCOptom

Role: PRINCIPAL_INVESTIGATOR

Centre for Ocular Research and Education (CORE)

Locations

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University of Waterloo School of Optometry & Vision Science

Waterloo, Ontario, Canada

Site Status

Countries

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Canada

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CV-23-36

Identifier Type: -

Identifier Source: org_study_id