Comparison of Somofilcon A Daily Disposable Test Contact Lens and Somofilcon A Daily Disposable Control Contact Lens

NCT ID: NCT03372551

Last Updated: 2019-07-23

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-29

Study Completion Date

2018-04-23

Brief Summary

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The purpose of this study is to investigate the overall clinical performance of the somofilcon A daily disposable test soft contact lens compared to the somofilcon A daily disposable control soft contact lens.

Detailed Description

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The purpose of this study is to evaluate the clinical performance of an investigational silicone-hydrogel contact lens (test) against a marketed silicone-hydrogel contact lens (control) when worn on a daily disposable wear modality over 1 week (for each lens) in a randomized, bilateral, cross-over, dispensing study.

Conditions

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Myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

This will be a, prospective, double-masked, randomized, bilateral, 1 week cross-over, dispensing study
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators
Both the participants and study investigators will be masked to the randomization schedule of the contact lenses used.

Study Groups

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somofilcon A 1 day test lens

Subjects wearing the somofilcon A 1 day test lens for one week, either randomized as the first or second pair.

Group Type EXPERIMENTAL

somofilcon A 1 day test lens

Intervention Type DEVICE

Contact lens

somofilcon A 1 day control lens

Intervention Type DEVICE

Contact lens

somofilcon A 1 day control lens

Subjects wearing the somofilcon A 1 day control lens for one week, either randomized as the first or second pair.

Group Type ACTIVE_COMPARATOR

somofilcon A 1 day test lens

Intervention Type DEVICE

Contact lens

somofilcon A 1 day control lens

Intervention Type DEVICE

Contact lens

Interventions

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somofilcon A 1 day test lens

Contact lens

Intervention Type DEVICE

somofilcon A 1 day control lens

Contact lens

Intervention Type DEVICE

Other Intervention Names

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somofilcon A daily disposable test soft contact lens Invigor I Test lens somofilcon A daily disposable control soft contact lens Select 1-Day Control lens

Eligibility Criteria

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Inclusion Criteria

* Is at least 17 years of age and has full legal capacity to volunteer;
* Has had a self-reported oculo-visual examination in the last two years;
* Has read, understood, and signed the information consent letter;
* Is willing and able to follow instructions and maintain the appointment schedule;
* Has a visual acuity of 20/30 or better (in each eye) with their habitual vision correction, or 20/20 best-corrected vision (for binocular distance acuity);
* Must be able to achieve 20/30 or better (in each eye) with the study lenses;
* Currently wears soft contact lenses for at least 3 days per week, 8 hours each day;
* Requires spectacle lens powers between -0.75 and -06.50 diopters sphere (0.25D steps);
* Has no more than 0.75 diopters of refractive astigmatism;
* Has clear corneas and no active\* ocular disease;
* Has not worn lenses for at least 12 hours before the examination.

Exclusion Criteria

* Is presently participating in any other clinical or research study including eye related clinical or research study;
* Has never worn contact lenses before.
* Has any systemic disease affecting ocular health.
* Has any active\* ocular pathology or severe insufficiency of lacrimal secretion (moderate to severe dry eyes) that would affect the wearing of contact lenses.
* Is using any systemic or topical medications that will affect a study outcome variable, and/or ocular health.
* Has any known sensitivity to fluorescein dye or products to be used in the study.
* Has persistent, clinically significant corneal or conjunctival staining using sodium fluorescein dye.
* Has any clinically significant lid or conjunctival abnormalities, active neovascularization or any central corneal scars.
* Is aphakic.
* Has undergone corneal refractive surgery.
* Is pregnant, lactating, or planning a pregnancy at the time of enrolment (by verbal confirmation at the screening visit).
Minimum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Center for Contact Lens Research, University of Waterloo

Waterloo, Ontario, Canada

Site Status

Countries

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Canada

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CV-16-43

Identifier Type: -

Identifier Source: org_study_id

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