Multi-Center Clinical Evaluation of Two Reusable Soft Contact Lenses

NCT ID: NCT02542072

Last Updated: 2017-10-24

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-08-31

Study Completion Date

2016-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to compare the subjective performance of comfilcon A lens against samfilcon A lens after 4 weeks of reusable lens wear.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This will be a 90 subject, randomized, bilateral, subject-masked, dispensing, cross-over study comparing comfilcon A versus samfilcon A lenses over 8 weeks of daily wear (2 x 4-weeks). Both eyes will wear the same lens (test or control) for 4 weeks in a randomized fashion. Subjects will be masked to lens type and investigators will be masked to the lens codes.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Myopia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

comfilcon A

Participants were randomized to wear the comfilcon A lens pair for one month during the cross over study.

Group Type ACTIVE_COMPARATOR

comfilcon A

Intervention Type DEVICE

contact lens

samfilcon A

Participants were randomized to wear the samfilcon A lens pair for one month during the cross over study.

Group Type ACTIVE_COMPARATOR

samfilcon A

Intervention Type DEVICE

contact lens

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

comfilcon A

contact lens

Intervention Type DEVICE

samfilcon A

contact lens

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Spherical distance Contact Lens prescription between -1.00 and -6.00D or +1.00 to +4.00D in both eyes (inclusive)
* Adapted soft Contact Lens wearers (i.e. \>1 month), daily disposable and reusable lens wearers.
* Spectacle cylinder 0.75D in both eyes.
* Correctable to 6/9 (20/30) in both eyes
* Be between 18 and 50 years of age (inclusive)
* Able to read, comprehend and sign an informed consent
* Own a mobile phone and be willing to respond to Short Message Service (SMS) survey
* Willing to comply with the wear and study visit schedule

Exclusion:

* Existing Biofinity or Ultra wearers
* Any active corneal infection, injury or inflammation
* Systemic or ocular allergies, which might interfere with Contact Lens wear
* Systemic disease, which might interfere with Contact Lens wear
* Ocular disease, which might interfere with Contact Lens wear
* Strabismus or amblyopia
* Subjects who have undergone corneal refractive surgery
* Subjects with keratoconus or other severe corneal irregularity contraindicating lens wear
* Pregnant or lactating
* Use of systemic/topical medication contraindicating Contact Lens wear
* Diabetic
* Site employees or family members of site employees
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Graeme Young

Role: PRINCIPAL_INVESTIGATOR

VisionCare

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Golden Optometric Group

Whittier, California, United States

Site Status

Complete Eye Care of Medina

Medina, Minnesota, United States

Site Status

Brock & Houlford

Chew Magna, Bristol, United Kingdom

Site Status

Tempany's Boutique Opticians

Broadstone, Dorset, United Kingdom

Site Status

David Gould Opticians

Rawtenstall, Lancashire, United Kingdom

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States United Kingdom

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

EX-MKTG-59 (VISA-406)

Identifier Type: -

Identifier Source: org_study_id