The Clinical Comparison of Somofilcon A 1 Day and Nelfilcon A Daily Disposable Contact Lenses

NCT ID: NCT04067141

Last Updated: 2020-11-24

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-07-04

Study Completion Date

2019-11-20

Brief Summary

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This subject-masked, randomized, bilateral crossover study will compare the clinical performance and subjective acceptance of the somofilcon A 1 day soft contact lens with the nelfilcon A daily disposable lens when used on a daily wear, daily disposable basis.

Detailed Description

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This will be a randomized, subject-masked, crossover, bilateral study, controlled by cross-comparison. This will compare the clinical performance and subjective acceptance of the somofilcon A 1 day soft contact lens with the nelfilcon A daily disposable lens when used on a daily wear, daily disposable basis.

Subjects will use each lens type for a week in random sequence. Follow-up visits for each lens will be performed after one week of wear. Lenses will be worn on a daily wear, daily disposable wear schedule.

Conditions

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Ametropia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

This is a bilateral crossover study
Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants

Study Groups

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somofilcon A, then nelfilcon A

Subjects will bilaterally wear the somofilcon A lenses, then crossover to nelfilcon A lenses after one week of wear. Both lenses will be worn on a daily wear basis for one week.

Group Type EXPERIMENTAL

somofilcon A

Intervention Type DEVICE

Contact Lens

nelfilcon A

Intervention Type DEVICE

Contact Lens

nelfilcon A, then somofilcon A

Subjects will bilaterally wear the nelfilcon A lenses, then crossover to somofilcon A lenses after one week of wear. Both lenses will be worn on a daily wear basis for one week.

Group Type EXPERIMENTAL

somofilcon A

Intervention Type DEVICE

Contact Lens

nelfilcon A

Intervention Type DEVICE

Contact Lens

Interventions

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somofilcon A

Contact Lens

Intervention Type DEVICE

nelfilcon A

Contact Lens

Intervention Type DEVICE

Other Intervention Names

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somofilcon A 1 day test lens clariti 1 day nelfilcon A Daily Disposable Contact Lens control lens DAILIES AquaComfort PLUS daily disposable

Eligibility Criteria

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Inclusion Criteria

* They are of legal age (18) and capacity to volunteer.
* They understand their rights as a research subject and are willing and able to sign a Statement of Informed Consent.
* They are willing and able to follow the protocol.
* They agree not to participate in other clinical research for the duration of this study.
* They have a contact lens spherical prescription between -1.00 to - 6.00D (inclusive)
* They have a maximum of -1.00DC ocular astigmatism in each eye.
* They can be satisfactorily fitted with the study lens types.
* At dispensing, they can attain at least 0.20 logMAR distance high contrast visual acuity in each eye with the study lenses within the available power range.
* They currently use soft contact lenses or have done so in the previous six months.
* They are willing to comply with the wear schedule (at least five days per week and for at least eight hours per day).
* They own a wearable pair of spectacles.

Exclusion Criteria

* They have an ocular disorder which would normally contra-indicate contact lens wear.
* They have a systemic disorder which would normally contra-indicate contact lens wear.
* They are using any topical medication such as eye drops or ointment.
* They have had cataract surgery.
* They have had corneal refractive surgery.
* They have any corneal distortion resulting from previous hard or rigid lens wear or have keratoconus.
* They are pregnant or breast-feeding.
* They have any ocular abnormality which would, in the opinion of the investigator, normally contraindicate contact lens wear.
* They have any infectious disease which would, in the opinion of the investigator, contraindicate contact lens wear or pose a risk to study personnel, or they have any immunosuppressive disease (e.g. HIV), or a history of anaphylaxis or severe allergic reaction.
* They have taken part in any other contact lens or care solution clinical trial or research, within two weeks prior to starting this study.
* They currently wear either the clariti 1day or the DAILIES AquaComfort Plus lens.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Eurolens Research

Manchester, , United Kingdom

Site Status

Countries

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United Kingdom

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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EX-MKTG-75

Identifier Type: -

Identifier Source: org_study_id