A Dispensing Clinical Trial of Test Contact Lens Against Marketed Contact Lens

NCT ID: NCT03499067

Last Updated: 2020-08-26

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

58 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-04-11

Study Completion Date

2018-08-01

Brief Summary

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Evaluation of the clinical performance of an investigational silicone-hydrogel contact lens (test) compared to a marketed lens (control), when worn on a daily basis for 1 month.

Detailed Description

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Evaluation of the clinical performance of an investigational silicone-hydrogel contact lens (test) compared to a marketed silicone- hydrogel contact lens (control), when worn on a daily basis for 1 month.

Conditions

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Myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Each subject will be randomized to wear the test or control contact lens for 1 month and then crossed-over to wear the other contact lens for 1 month.
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators
This will be a double-masked study in which both participant and investigator will be masked.

Study Groups

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Test lens

Subjects wearing the test contact lens either as first or second pair during the cross-over study.

Group Type EXPERIMENTAL

Test lens

Intervention Type DEVICE

Contact lens

Control lens

Intervention Type DEVICE

Contact lens

Control lens

Subjects wearing the control contact lens either as first or second pair during the cross-over study.

Group Type ACTIVE_COMPARATOR

Test lens

Intervention Type DEVICE

Contact lens

Control lens

Intervention Type DEVICE

Contact lens

Interventions

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Test lens

Contact lens

Intervention Type DEVICE

Control lens

Contact lens

Intervention Type DEVICE

Other Intervention Names

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Invigor I lens Clariti lens

Eligibility Criteria

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Inclusion Criteria

* Has had a self-reported oculo-visual examination in the last two years.
* Is at least 18 years of age and has full legal capacity to volunteer.
* Has read and understood the information consent letter.
* Is willing and able to follow instructions and maintain the appointment schedule.
* Is correctable to a visual acuity of 20/40 or better (in each eye) with their habitual vision correction or 20/20 best-corrected.
* Currently wears soft contact lenses.
* Requires spectacle lens powers between -0.75 to -6.50 diopters sphere (0.25D steps).
* Has no more than 0.75 diopters of refractive astigmatism.
* Has clear corneas and no active ocular disease.
* Has not worn lenses for at least 12 hours before the examination.
* Has a usable pair of spectacle lenses if required for transportation to the site for the initial visit

Exclusion Criteria

* Has never worn contact lenses before.
* Has any systemic disease affecting ocular health.
* Is using any systemic or topical medications that will affect ocular health.
* Has any ocular pathology or severe insufficiency of lacrimal secretion (moderate to severe dry eyes) that would affect the wearing of contact lenses.
* Has persistent, clinically significant corneal or conjunctival staining using sodium fluorescein dye.
* Has any clinically significant lid or conjunctival abnormalities, active neovascularization or any central corneal scars.
* Is aphakic.
* Has undergone corneal refractive surgery.
* Is participating in any other type of eye related clinical or research study.
* Known allergy to a product used in this study (ex. Shellfish allergy)
* Is pregnant, lactating or planning a pregnancy at the time of enrolment (by verbal confirmation at the screening visit).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Clinical Research Center, University of California, Berkeley

Berkeley, California, United States

Site Status

Clinical Optics Research Lab (CORL) Indiana University School of Optometry, Indiana University

Bloomington, Indiana, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CV-18-07

Identifier Type: -

Identifier Source: org_study_id

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