Sedentary Behavior Breaks With Isometric Exercise in Cardiovascular Health Indicators

NCT ID: NCT03949205

Last Updated: 2021-09-29

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 17 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-05-13
• Study Completion Date: 2021-02-20

Brief Summary

The goal of this study is to analyze the chronic effects of sedentary behavior breaks using the leg extension isometric exercise in the cardiovascular health indicators of healthy adults exposed to prolonged time in the sitting position. The patients recruited will be randomized into two groups: leg extension isometric training (TIE) and control group (CG). The TIE group will perform 12 weeks of isometric training. The CG will be advised not to change their routine activities, especially diet and physical activities.In the pre and post-intervention periods cardiovascular measures will be obtained.

Detailed Description

Long periods in sedentary behavior promote deterioration of vascular function, which is directly associated with the occurence of chronic noncommunicable diseases. In this context, the execution of interruptions in this behavior (breaks) is recommended. Studies have shown benefits of isometric training in vascular function, which could be useful to minimize the consequences of time spent in sedentary behavior. Thus, the goal of this study is to analyze the chronic effects of sedentary behavior breaks using leg extension isometric exercise in the cardiovascular health indicators of adults exposed to prolonged time in the sitting position. The target population of the study will consist of healthy subjects above 18 years of age of both genders. All subjects will be submitted to measurements of endothelial function, blood pressure and cardiac autonomic modulation. After these measurements, the subjects will be randomized into two groups: leg extension isometric training group (TIE) and control group (CG). After 12 weeks both groups will be submitted to the same measurements from pre-intervention.

Conditions

Sedentary Behavior

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Leg Extension Isometric Training

Experimental group will perform leg extension isometric exercise.

Group Type: EXPERIMENTAL

Leg Extension Isometric Training

Intervention Type: OTHER

The leg extension isometric exercise will be performed tree times a week , in four 2 min bouts of isometric contraction, at a intensity of 30% of maximal voluntary contraction and an interval of two minutes between bouts.

Control Group

Control group will be advised to maintain their work habits and not to change their routine activities, especially diet and physical activities.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Leg Extension Isometric Training

The leg extension isometric exercise will be performed tree times a week , in four 2 min bouts of isometric contraction, at a intensity of 30% of maximal voluntary contraction and an interval of two minutes between bouts.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• No diagnostic of cardiovascular diseases or diabetes
• Do not present high cardiovascular risk
• Do not participate in an exercise program in the previous six months
• Occupational activity that requires more than six hours of sitting time per day
• Do not be a smoker or make use of medications

Exclusion Criteria

• Adherence to the training sessions inferior to 85%
• Adherence to another supervised exercise program
• Change the characteristics of the occupational activities

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Nove de Julho

OTHER

Sponsor Role: lead

Responsible Party

Raphael Mendes Ritti Dias

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Raphael Ritti-Dias, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Nove de Julho

Locations

Universidade Nove de Julho

São Paulo, , Brazil

Countries

Brazil

Other Identifiers

BREAK001

Identifier Type: -

Identifier Source: org_study_id