Acute Cardiovascular Responses and Chronic Adaptations of Strength Exercise in Intermittent Claudication Patients

NCT ID: NCT02778568

Last Updated: 2016-05-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2015-12-31

Brief Summary

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The aim of this study was to analyze the effects of resistance exercise and training on cardiovascular function of peripheral artery disease patients.

Detailed Description

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Several studies have shown that strength training can promote important benefits for the cardiovascular system in healthy subjects and patients with chronic diseases. However, the effects of resistance exercise on cardiovascular function in intermittent claudication patients are unclear. In addition, it also do not know the chronic effects on cardiovascular function in these patients.

Conditions

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Peripheral Artery Disease Intermittent Claudication

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Resistance Training

Patients performed resistance exercises

Group Type EXPERIMENTAL

Resistance training

Intervention Type BEHAVIORAL

Resistance training exercises

Control

Patients who performed flexibility exercise

Group Type ACTIVE_COMPARATOR

Control

Intervention Type BEHAVIORAL

Stretching exercises

Interventions

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Resistance training

Resistance training exercises

Intervention Type BEHAVIORAL

Control

Stretching exercises

Intervention Type BEHAVIORAL

Other Intervention Names

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Physical training

Eligibility Criteria

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Inclusion Criteria

* Had a graded treadmill test that was limited by claudication (2 minutes)
* Had an ankle brachial index \<0.90
* Had systolic blood pressure ,160 mmHg and/or diastolic blood pressure,105 mmHg
* Were not performing any regular exercise program
* Were not using antihypertensive medications affecting the heart rate (e.g., b-blockers and nondihydropyridine calcium channel blockers)
* Were nonobese
* Individuals who have not undergone bypass surgery or angioplasty least one year ago

Exclusion Criteria

* Had no symptoms related to myocardial ischemia during the treadmill test
* Amputation
Minimum Eligible Age

50 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fundação de Amparo à Ciência e Tecnologia de Pernambuco

OTHER

Sponsor Role collaborator

Conselho Nacional de Desenvolvimento Científico e Tecnológico

OTHER_GOV

Sponsor Role collaborator

University of Pernambuco

OTHER

Sponsor Role lead

Responsible Party

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Raphael M. Ritti Dias

Full Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marilia A Correia, MS

Role: STUDY_CHAIR

University of Pernambuco

Locations

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Emergency Hospital of Pernambuco - PROCAPE

Recife, Pernambuco, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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RMR2013FCPE MOVED

Identifier Type: -

Identifier Source: org_study_id

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