Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot Study
NCT ID: NCT03921931
Last Updated: 2025-05-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
35 participants
INTERVENTIONAL
2018-11-26
2026-05-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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healthy volunteers
light stimulation
White light stimulation
Stimulation of the retina with white light
primary open angle glaucoma patients
light stimulation
White light stimulation
Stimulation of the retina with white light
age-related macular degeneration patients
light stimulation
White light stimulation
Stimulation of the retina with white light
Interventions
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White light stimulation
Stimulation of the retina with white light
Eligibility Criteria
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Inclusion Criteria
* signed informed consent form
* ametropia below 3 diopters
* ability and willingness to follow instructions
for healthy volunteers:
* normal ophthalmologic findings
for primary open angle glaucoma patients (POAG):
* diagnosed POAG
* MD \<= 10 dB
for age-related macular degeneration (AMD):
* diagnosed dry AMD
* diagnosed stage II or stage III AMD
Exclusion Criteria
* Ocular inflammation and ocular disease interfering with the study aims
* Use of photosensitizing medication (phototoxic drugs, photoallergic drugs) in the 3 months preceding the study
* Presence of any condition with the possibility of causing photosensitivity, including systemic lupus erythematosus SLE, Porphyria, Vitiligo, Xeroderma Pigmentosum and Albinism
* Presence of any form of epilepsy
* Ocular surgery in the 3 months preceding the study
* Pregnancy, planned pregnancy or lactating
* Any medical or surgical history, disorder or disease such as acute or chronic severe organic disease
18 Years
ALL
Yes
Sponsors
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Medical University of Vienna
OTHER
Responsible Party
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Doreen Schmidl
Associate Professor, MD, PhD
Principal Investigators
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Doreen Schmidl, MD,PhD
Role: PRINCIPAL_INVESTIGATOR
Department of Clinical Pharmacology, Medical University of Vienna
Locations
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Medical University of Vienna, Department of Clinical Pharmacology
Vienna, Vienna, Austria
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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OPHT-050418
Identifier Type: -
Identifier Source: org_study_id
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