Identification of Risk Factors for Atrial Fibrillation After Ablation of an Atrial Flutter by Radiofrequency of the Cavotricuspid Isthmus.

NCT ID: NCT03919097

Last Updated: 2022-07-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-08

Study Completion Date

2019-11-20

Brief Summary

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Atrial flutter is a common condition that is effectively treated by ablation using radiofrequency. Due to its feasibility, effectiveness and low procedural risk, radiofrequency ablation is a first-line treatment of atrial flutter.

Several studies have been published concerning the factors associated with the occurrence of atrial fibrillation during or after flutter ablation, in patients with and without clinical history of atrial fibrillation. 26 to 46% of patients are likely to develop it, according to ECG or Holter diagnoses. The figure rises to more than 50% with a diagnosis with an implantable loop recorder.

In patients without a prior history of atrial fibrillation before ablation, anticoagulants are routinely administered 4-6 weeks after flutter removal by most cardiologists.

Although there are no specific guidelines for anticoagulation after flutter ablation, it is currently recommended to treat the patient as for atrial fibrillation. It is therefore crucial to identify in advance patients at high risk of atrial fibrillation after flutter ablation, in order to assess the appropriateness of maintaining oral anticoagulant therapy.

The objectives of this study are:

* to evaluate the frequency and identify the factors predicting the occurrence of atrial fibrillation after flutter ablation
* to determine the risk of a stroke occurring in patients with atrial fibrillation after flutter ablation.

The database consists in patients of the CHU Brugmann Hospital treated between 1996 and 2018.

Detailed Description

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Conditions

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Flutter

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Control

No atrial arrhythmia post-ablation of a flutter by radiofrequency of the isthmus of the cavotricuspid valva.

Medical Data extraction

Intervention Type OTHER

Data extraction from the patient's Medical Files

Atrial fibrillation post ablation

Atrial arrhythmia (Atrial Fibrillation) post-ablation of a flutter by radiofrequency of the isthmus of the cavotricuspid valva.

Medical Data extraction

Intervention Type OTHER

Data extraction from the patient's Medical Files

Flutter recidive

Recidive of the flutter after ablation.

Medical Data extraction

Intervention Type OTHER

Data extraction from the patient's Medical Files

Atrial Fibrillation antecedents

Patients with atrial fibrillation after flutter ablation, with previous antecedents of atrial fibrillation.

Medical Data extraction

Intervention Type OTHER

Data extraction from the patient's Medical Files

No Atrial Fibrillation antecedents

Patients with atrial fibrillation after flutter ablation, without antecedents of atrial fibrillation.

Medical Data extraction

Intervention Type OTHER

Data extraction from the patient's Medical Files

Interventions

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Medical Data extraction

Data extraction from the patient's Medical Files

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Patients treated at the CHU Brugmann Hospital for flutter ablation by radiofrequency between 1996 and 2018.

Exclusion Criteria

None
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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José Castro

OTHER

Sponsor Role lead

Responsible Party

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José Castro

Head of cardiology clinic

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Georges Fayad, MD

Role: PRINCIPAL_INVESTIGATOR

CHU Brugmann

Locations

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CHU Brugmann

Brussels, , Belgium

Site Status

Countries

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Belgium

Other Identifiers

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CHUB-Fayad

Identifier Type: -

Identifier Source: org_study_id

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