Ovarian Reserve in Crohn's Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-03-01

Study Completion Date

2019-09-01

Brief Summary

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Crohn's disease reduces fertility by inducing inflammation both directly and in the fallopian tubes and ovaries and indirectly through surgical interventions and tubal adhesions associated with disease treatment. Anti-mullerian hormone (AMH) is a reliable indicator of ovarian reserve in women. The aim of this study was to compare serum AMH levels in women with Crohn's disease and healthy controls. In this study, the investigators aimed to investigate AMH and ovarian capacity in the study group with crohn's disease and in the control group without disease.

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Detailed Description

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Conditions

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Crohn Disease Ovary Disease Anti-Mullerian Hormone Deficiency

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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study group

women in reproductive age with crohn's disease

AMH levels in young women with crohn's disease will be considered.

Intervention Type OTHER

Ovarian Reserve in Young Women of Reproductive Age with Crohn's Disease;Blood will be taken from both the study and control groups and the AMH level will be evaluated.

control group

women in reproductive age without crohn's disease,

AMH levels in young women with crohn's disease will be considered.

Intervention Type OTHER

Ovarian Reserve in Young Women of Reproductive Age with Crohn's Disease;Blood will be taken from both the study and control groups and the AMH level will be evaluated.

Interventions

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AMH levels in young women with crohn's disease will be considered.

Ovarian Reserve in Young Women of Reproductive Age with Crohn's Disease;Blood will be taken from both the study and control groups and the AMH level will be evaluated.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* crohn's disease;
* reproductive age women

Exclusion Criteria

* Over 40 years old,
* a previous ovarian resection;
* renal failure (serum creatinine levels N1.2 mg / dL);suspicion of malignancy;
* the presence of hereditary or acquired hematological disease;
* pregnancy;
* current lactation;
* the presence of a serious comorbid chronic disease;
* cirrhosis originating from chronic liver disease;
* abnormal thyroid function tests;
* a known serious psychological problem;
* presence of alcoholism and male sex.

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes