Association of Plasma PTX3 Concentration and Outcomes of STEMI

NCT ID: NCT03894176

Last Updated: 2019-03-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

335 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2018-09-02

Brief Summary

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335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method. The angiographic and clinical outcomes were evaluated according to the PTX3 concentration.

Detailed Description

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335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method using human PTX3 kit. Blood was drawn at the emergency department before primary PCI. The angiographic and clinical outcomes were evaluated and analyzed according to the PTX3 concentration. The angiographic outcome were thrombus grade on initial angiogram and final TIMI flow. The clinical outcome were ECG resolution after primary PCI and all-cause death at 30 days. The plasma PTX3 concentration was then compared based on the outcomes.

Conditions

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STEMI Coronary; Ischemic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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PTX3 concentration

First quartile, second quartile, third quartile and fourth quartile of PTX3 in ng/mL

Plasma PTX3 concentration

Intervention Type OTHER

Long pentraxin 3, thrombus burden, final TIMI flow, ST segment resolution, STEMI, primary PCI

Interventions

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Plasma PTX3 concentration

Long pentraxin 3, thrombus burden, final TIMI flow, ST segment resolution, STEMI, primary PCI

Intervention Type OTHER

Other Intervention Names

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PTX3

Eligibility Criteria

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Inclusion Criteria

* Patients with acute STEMI with symptom onset \<12 h undergoing primary PCI

Exclusion Criteria

* Acute STEMI patients who received fibrinolytic therapy
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Indonesian Cardiovascular Research Center

OTHER

Sponsor Role lead

Responsible Party

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Surya Dharma

Primary Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Indonesian Cardiovascular Research Center

Jakarta, DKI Jakarta, Indonesia

Site Status

Countries

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Indonesia

Other Identifiers

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IndonesianCRC

Identifier Type: -

Identifier Source: org_study_id

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