Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
ACTIVE_NOT_RECRUITING
NA
82 participants
INTERVENTIONAL
2016-07-21
2027-12-01
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Inflammatory and Metabolic Responses to Long-term Dietary Supplementation With Anthocyanin-rich Blend
NCT04637945
Creatine Monohydrate Supplementation and Vascular Endothelial Health
NCT05014659
Radicle Energy2: A Study of Health and Wellness Products on Fatigue and Other Health Outcomes
NCT06074627
Radicle Energy 25: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes
NCT07036679
Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma
NCT01897792
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
White blood cells are essential for the immune response and rely on the mitochondria to carry out important cell functions. The Principal Investigator's current research shows that patients with calcium oxalate kidney stones have decreased mitochondrial function in their immune cells. Using the expertise of the investigators, this study will test whether oxalate has a direct effect on mitochondrial function in immune cells from healthy subjects. This information could help us understand the role of oxalate on the immune system during kidney stone pathogenesis.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
3d Diet+Spinach Smoothie+Breakfast
3 days of prepared meals with fasting on the final day. On final day, participants will return to study site and drink a prepared blended spinach smoothie and be provided a breakfast meal.
Breakfast
a prepared meal consisting of pastry and 2 cooked egg whites
Spinach smoothie
a prepared blended spinach smoothie, consisting of banana, avocado, orange juice, and spinach
5d Diet+Spinach Smoothie+Breakfast
5 days of prepared meals with fasting on the final day. On final day, participants will return to the study site and drink a prepared blended spinach smoothie and be provided a breakfast meal.
Breakfast
a prepared meal consisting of pastry and 2 cooked egg whites
Spinach smoothie
a prepared blended spinach smoothie, consisting of banana, avocado, orange juice, and spinach
3d Diet+Kale Smoothie+Breakfast
3 days of prepared meals with fasting on the final day. On the final day, participants will return to the study site and drink a prepared kale smoothie and be provided a breakfast meal.
Breakfast
a prepared meal consisting of pastry and 2 cooked egg whites
Kale smoothie
prepared blended kale smoothie, consisting of banana, avocado, orange juice, and kale
3d Diet+V Spinach Smoothie+Breakfast
3 days of prepared meals with fasting on the final day. On final day, participants will return to the study site and drink a prepared blended spinach smoothie with varying amounts of spinach and be provided a breakfast meal.
Breakfast
a prepared meal consisting of pastry and 2 cooked egg whites
V spinach smoothie
a prepared blended spinach smoothie, consisting of banana, avocado, orange juice, and a varying amount (low, medium, high) of spinach
3d Diet+Blended Smoothie+Breakfast
3 days of prepared meals with fasting on the final day. On final day, participants will return to the study site and drink a prepared blended smoothie and be provided a breakfast meal.
Breakfast
a prepared meal consisting of pastry and 2 cooked egg whites
Blended smoothie
a prepared blended smoothie, consisting of banana, avocado, and orange juice
3d Diet+Breakfast
3 days of prepared meals with fasting on the final day. On final day, participants will return to the study site and be provided a breakfast meal.
Breakfast
a prepared meal consisting of pastry and 2 cooked egg whites
3d Diet+Sodium Oxalate Drink+Breakfast
3 days of prepared meals with fasting on the final day. On final day, participants will return to the study site and drink a prepared sodium oxalate drink and be provided a breakfast meal.
Breakfast
a prepared meal consisting of pastry and 2 cooked egg whites
Sodium oxalate drink
a prepared sodium oxalate drink
3d Diet+Spinach Smoothie+Breakfast w/ 24 Hr Urine
3 days of prepared meals with fasting on the final day. On final day, participants will return to the study site and drink a blended spinach smoothie and be provided a breakfast meal.
Breakfast
a prepared meal consisting of pastry and 2 cooked egg whites
Spinach smoothie
a prepared blended spinach smoothie, consisting of banana, avocado, orange juice, and spinach
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Breakfast
a prepared meal consisting of pastry and 2 cooked egg whites
Spinach smoothie
a prepared blended spinach smoothie, consisting of banana, avocado, orange juice, and spinach
Kale smoothie
prepared blended kale smoothie, consisting of banana, avocado, orange juice, and kale
Blended smoothie
a prepared blended smoothie, consisting of banana, avocado, and orange juice
V spinach smoothie
a prepared blended spinach smoothie, consisting of banana, avocado, orange juice, and a varying amount (low, medium, high) of spinach
Sodium oxalate drink
a prepared sodium oxalate drink
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Male or Female
* Age 18 to 70 years
* Non-tobacco users
* BMI between 19 and 27
* Willingness to abstain from vigorous exercise during study period
* Normal blood comprehensive metabolic panel
Exclusion Criteria
* Pregnant females
* Active medical problems
* History of kidney stones
* Any medical disorder that could influence absorption or excretion of oxalate
* BMI less than 19 or greater than 27
* Tobacco users
* Current use of medications or dietary supplements
18 Years
70 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Alabama at Birmingham
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Tanecia Mitchell, PhD
Principal Investigator
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Tanecia Mitchell, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Alabama at Birmingham
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of Alabama at Birmingham
Birmingham, Alabama, United States
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Kumar P, Patel M, Oster RA, Yarlagadda V, Ambrosetti A, Assimos DG, Mitchell T. Dietary Oxalate Loading Impacts Monocyte Metabolism and Inflammatory Signaling in Humans. Front Immunol. 2021 Feb 25;12:617508. doi: 10.3389/fimmu.2021.617508. eCollection 2021.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
F151123009
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.