Auditory Training With Speech Related Acoustic Cues Using Psychophysical Testing

NCT ID: NCT03867032

Last Updated: 2023-04-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2022-12-31

Study Completion Date

2023-06-30

Brief Summary

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In this study, the investigators will evaluate whether auditory training with speech-related acoustic features in psychophysical testing will help CI subjects improve speech recognition. The primary endpoint is the speech recognition measures.

Detailed Description

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Conditions

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Deafness

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Cochlear implant users

The group will receive auditory training (psychophysical), and will be evaluated for speech recognition to determine the effect of training.

Group Type EXPERIMENTAL

Auditory training

Intervention Type BEHAVIORAL

Training with psychophysical tests (amplitude modulation detection on single electrodes) for improving speech recognition

Interventions

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Auditory training

Training with psychophysical tests (amplitude modulation detection on single electrodes) for improving speech recognition

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Native speakers of English
* Cochlear Nucleus cochlear implant users or Advanced Bionics users
* Postlingually deafened
* Has had device experience for at least one year
* Can be child or adult at the time of enrollment

Exclusion Criteria

* None
Minimum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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East Carolina University

OTHER

Sponsor Role lead

Responsible Party

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Heather Wright

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Banai K, Hornickel J, Skoe E, Nicol T, Zecker S, Kraus N. Reading and subcortical auditory function. Cereb Cortex. 2009 Nov;19(11):2699-707. doi: 10.1093/cercor/bhp024. Epub 2009 Mar 17.

Reference Type BACKGROUND
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Baumann S, Joly O, Rees A, Petkov CI, Sun L, Thiele A, Griffiths TD. The topography of frequency and time representation in primate auditory cortices. Elife. 2015 Jan 15;4:e03256. doi: 10.7554/eLife.03256.

Reference Type BACKGROUND
PMID: 25590651 (View on PubMed)

Boebinger D, Evans S, Rosen S, Lima CF, Manly T, Scott SK. Musicians and non-musicians are equally adept at perceiving masked speech. J Acoust Soc Am. 2015 Jan;137(1):378-87. doi: 10.1121/1.4904537.

Reference Type BACKGROUND
PMID: 25618067 (View on PubMed)

Chen JK, Chuang AY, McMahon C, Hsieh JC, Tung TH, Li LP. Music training improves pitch perception in prelingually deafened children with cochlear implants. Pediatrics. 2010 Apr;125(4):e793-800. doi: 10.1542/peds.2008-3620. Epub 2010 Mar 8.

Reference Type BACKGROUND
PMID: 20211951 (View on PubMed)

Coffey EBJ, Mogilever NB, Zatorre RJ. Speech-in-noise perception in musicians: A review. Hear Res. 2017 Sep;352:49-69. doi: 10.1016/j.heares.2017.02.006. Epub 2017 Feb 14.

Reference Type BACKGROUND
PMID: 28213134 (View on PubMed)

Fritz J, Elhilali M, Shamma S. Active listening: task-dependent plasticity of spectrotemporal receptive fields in primary auditory cortex. Hear Res. 2005 Aug;206(1-2):159-76. doi: 10.1016/j.heares.2005.01.015.

Reference Type BACKGROUND
PMID: 16081006 (View on PubMed)

Fitzgerald MB, Wright BA. Perceptual learning and generalization resulting from training on an auditory amplitude-modulation detection task. J Acoust Soc Am. 2011 Feb;129(2):898-906. doi: 10.1121/1.3531841.

Reference Type BACKGROUND
PMID: 21361447 (View on PubMed)

Fu QJ, Galvin JJ 3rd, Wang X, Wu JL. Benefits of music training in mandarin-speaking pediatric cochlear implant users. J Speech Lang Hear Res. 2015 Feb;58(1):163-9. doi: 10.1044/2014_JSLHR-H-14-0127.

Reference Type BACKGROUND
PMID: 25321148 (View on PubMed)

Huyck JJ, Wright BA. Learning, worsening, and generalization in response to auditory perceptual training during adolescence. J Acoust Soc Am. 2013 Aug;134(2):1172-82. doi: 10.1121/1.4812258.

Reference Type BACKGROUND
PMID: 23927116 (View on PubMed)

Looi V, Gfeller K, Driscoll V. MUSIC APPRECIATION AND TRAINING FOR COCHLEAR IMPLANT RECIPIENTS: A REVIEW. Semin Hear. 2012 Nov 1;33(4):307-334. doi: 10.1055/s-0032-1329222. Epub 2012 Nov 19.

Reference Type BACKGROUND
PMID: 23459244 (View on PubMed)

Parbery-Clark A, Skoe E, Kraus N. Musical experience limits the degradative effects of background noise on the neural processing of sound. J Neurosci. 2009 Nov 11;29(45):14100-7. doi: 10.1523/JNEUROSCI.3256-09.2009.

Reference Type BACKGROUND
PMID: 19906958 (View on PubMed)

Patel AD. Why would Musical Training Benefit the Neural Encoding of Speech? The OPERA Hypothesis. Front Psychol. 2011 Jun 29;2:142. doi: 10.3389/fpsyg.2011.00142. eCollection 2011.

Reference Type BACKGROUND
PMID: 21747773 (View on PubMed)

Polley DB, Steinberg EE, Merzenich MM. Perceptual learning directs auditory cortical map reorganization through top-down influences. J Neurosci. 2006 May 3;26(18):4970-82. doi: 10.1523/JNEUROSCI.3771-05.2006.

Reference Type BACKGROUND
PMID: 16672673 (View on PubMed)

Ruggles DR, Freyman RL, Oxenham AJ. Influence of musical training on understanding voiced and whispered speech in noise. PLoS One. 2014 Jan 28;9(1):e86980. doi: 10.1371/journal.pone.0086980. eCollection 2014.

Reference Type BACKGROUND
PMID: 24489819 (View on PubMed)

Sabin AT, Eddins DA, Wright BA. Perceptual learning evidence for tuning to spectrotemporal modulation in the human auditory system. J Neurosci. 2012 May 9;32(19):6542-9. doi: 10.1523/JNEUROSCI.5732-11.2012.

Reference Type BACKGROUND
PMID: 22573676 (View on PubMed)

Szpiro SF, Wright BA, Carrasco M. Learning one task by interleaving practice with another task. Vision Res. 2014 Aug;101:118-24. doi: 10.1016/j.visres.2014.06.004. Epub 2014 Jun 21.

Reference Type BACKGROUND
PMID: 24959653 (View on PubMed)

Wright BA, Sabin AT, Zhang Y, Marrone N, Fitzgerald MB. Enhancing perceptual learning by combining practice with periods of additional sensory stimulation. J Neurosci. 2010 Sep 22;30(38):12868-77. doi: 10.1523/JNEUROSCI.0487-10.2010.

Reference Type BACKGROUND
PMID: 20861390 (View on PubMed)

Yucel E, Sennaroglu G, Belgin E. The family oriented musical training for children with cochlear implants: speech and musical perception results of two year follow-up. Int J Pediatr Otorhinolaryngol. 2009 Jul;73(7):1043-52. doi: 10.1016/j.ijporl.2009.04.009. Epub 2009 May 2.

Reference Type BACKGROUND
PMID: 19411117 (View on PubMed)

Other Identifiers

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Zhou_R01_study5

Identifier Type: -

Identifier Source: org_study_id

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