Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
NA
INTERVENTIONAL
2021-12-31
2023-12-31
Brief Summary
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Light sedation and Pressure Support ventilation is feasible in ARDS patients. However spontaneous breathing can lead to high transpulmonary pressure.
The goal of the study is to measure transpulmonary pressure before sedation decrease and after stabilization. The main endpoint is transpulmonary pressure less than 24 cmH2O.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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light sedation pressure support ventilation
decrease of sedation doses and switch of ventilator settings
tapering sedation doses (propofol) switch from assisted ventilation to pressure support ventilation
Interventions
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decrease of sedation doses and switch of ventilator settings
tapering sedation doses (propofol) switch from assisted ventilation to pressure support ventilation
Eligibility Criteria
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Inclusion Criteria
* social insurance
Exclusion Criteria
* pregnancy
* need for muscular paralysis
* need for deep neurosedation
* more than 24hrs of artificial ventilation
* cystic fibrosis
18 Years
ALL
No
Sponsors
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University Hospital, Lille
OTHER
Responsible Party
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Principal Investigators
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Geoffrey Ledoux, MD
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Lille
Other Identifiers
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2018-A01036-49
Identifier Type: OTHER
Identifier Source: secondary_id
2017_18
Identifier Type: -
Identifier Source: org_study_id
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